APLNR inhibited nasopharyngeal carcinoma growth and immune escape by downregulating PD-L1.

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第一作者： Ying,Liu

第一单位： Department of Medical Laboratory Science, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China; Department of Medical Laboratory Science, Xiangya School of Medicine, Central South University, Changsha, Hunan, China.

作者： Ying,Liu ^[1] ; Nan,Li ^[1] ; Yilin,Guo ^[1] ; Qing,Zhou ^[2] ; Yuqin,Yang ^[3] ; Jiaxue,Lu ^[1] ; Ziying,Tian ^[1] ; Jieyu,Zhou ^[1] ; Shiqi,Yan ^[1] ; Xiayu,Li ^[4] ; Lei,Shi ^[5] ; Su,Jiang ^[1] ; Junshang,Ge ^[6] ; Ranran,Feng ^[7] ; Donghai,Huang ^[8] ; Zhaoyang,Zeng ^[6] ; Songqing,Fan ^[5] ; Wei,Xiong ^[6] ; Guiyuan,Li ^[6] ; Wenling,Zhang ^[9]

作者单位： Department of Medical Laboratory Science, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China; Department of Medical Laboratory Science, Xiangya School of Medicine, Central South University, Changsha, Hunan, China. ^[1] Department of Clinical Laboratory, First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China. ^[2] Shenzhen Maternity &Child Healthcare Hospital Clinical Laboratory, Shenzhen, Guangdong, China. ^[3] Hunan Key Laboratory of Nonresolving Inflammation and Cancer, Disease Genome Research Center, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China. ^[4] Department of Pathology, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China. ^[5] NHC Key Laboratory of Carcinogenesis, Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, China; The Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Cancer Research Institute and School of Basic Medicine Sciences, Central South University, Changsha, Hunan, China. ^[6] Department of Andrology, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha, Hunan, China. ^[7] Department of Otolaryngology, Xiangya Hospital, Central South University, Changsha, Hunan, China. ^[8] Department of Medical Laboratory Science, the Third Xiangya Hospital, Central South University, Changsha, Hunan, China; Department of Medical Laboratory Science, Xiangya School of Medicine, Central South University, Changsha, Hunan, China. Electronic address: zhangwenling@csu.edu.cn. ^[9]

关键词 APLNR IFN-γ Immune Escape Nasopharyngeal Carcinoma PD-L1