NOD2 activation enhances macrophage Fcγ receptor function and may increase the efficacy of antibody therapy.

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第一作者： Giovanna,Merchand-Reyes

第一单位： Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH, United States.

作者： Giovanna,Merchand-Reyes ^[1] ; Mikayla F,Bull ^[2] ; Ramasamy,Santhanam ^[1] ; Maria L,Valencia-Pena ^[1] ; Rakesh A,Murugesan ^[2] ; Aadesh,Chordia ^[2] ; Xiaokui-Molly,Mo ^[3] ; Frank H,Robledo-Avila ^[4] ; Juan De Dios,Ruiz-Rosado ^[5] ; William Edgar,Carson ^[6] ; John C,Byrd ^[7] ; Jennifer A,Woyach ^[1] ; Susheela,Tridandapani ^[1] ; Jonathan P,Butchar ^[1]

作者单位： Division of Hematology, Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH, United States. ^[1] College of Medicine, The Ohio State University, Columbus, OH, United States. ^[2] Department of Biomedical Informatics, The Ohio State University, Columbus, OH, United States. ^[3] Center for Microbial Pathogenesis, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, United States. ^[4] Kidney and Urinary Tract Center, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, United States.;Division of Pediatric Nephrology and Hypertension, Nationwide Children's Hospital, Columbus, OH, United States. ^[5] Department of Surgery, The Ohio State University, Columbus, OH, United States. ^[6] Department of Internal Medicine, College of Medicine, University of Cincinnati, Cincinnati, OH, United States. ^[7]

关键词 NOD2 agonists antibody-mediated responses chronic lymphocytic leukemia monocytes pre-clinical model