Myelin-reactive B cells exacerbate CD4<sup>+</sup> T cell-driven CNS autoimmunity in an IL-23-dependent manner.

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作者： Mohamed Reda,Fazazi ^[1] ; Prenitha Mercy Ignatius Arokia,Doss ^[1] ; Resel,Pereira ^[2] ; Neva,Fudge ^[3] ; Aryan,Regmi ^[4] ; Charles,Joly-Beauparlant ^[2] ; Irshad,Akbar ^[5] ; Asmita Pradeep,Yeola ^[6] ; Benoit,Mailhot ^[1] ; Joanie,Baillargeon ^[1] ; Philippe,Grenier ^[1] ; Nicolas,Bertrand ^[1] ; Steve,Lacroix ^[6] ; Arnaud,Droit ^[6] ; Craig S,Moore ^[7] ; Olga L,Rojas ^[1] ; Manu,Rangachari ^[8]

作者单位： axe Neurosciences, Centre de recherche du Centre hospitalier universitaire (CHU) de Québec - Université Laval, Pavillon CHUL, 2705 boul Laurier, Quebec City, G1V 4G2, QC, Canada. ^[1] Krembil Research Institute, University Health Network, Toronto, M5T 0S8, ON, Canada. ^[2] Division of BioMedical Sciences, Memorial University of Newfoundland, St. John's, NL, A1B 3V6, Canada. ^[3] Department of Neurology, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, A1B 3V6, Canada. ^[4] Department of Immunology, University of Toronto, Toronto, M5S 1A1, ON, Canada. ^[5] axe Endocrinologie et nephrologie, Centre de recherche du Centre hospitalier universitaire (CHU) de Québec - Université Laval, Pavillon CHUL, 2705 boul Laurier, Quebec City, QC, G1V 4G2, Canada. ^[6] Faculty of Pharmacy, Laval University, 1050 ave de la Médecine, Quebec City, QC, G1V 4G2, Canada. ^[7] Department of Molecular Medicine, Faculty of Medicine, Laval University, 1050 ave de la Médecine, Quebec City, QC, G1V 4G2, Canada. ^[8] axe Neurosciences, Centre de recherche du Centre hospitalier universitaire (CHU) de Québec - Université Laval, Pavillon CHUL, 2705 boul Laurier, Quebec City, G1V 4G2, QC, Canada. manu.rangachari@crchudequebec.ulaval.ca. ^[9] Department of Molecular Medicine, Faculty of Medicine, Laval University, 1050 ave de la Médecine, Quebec City, QC, G1V 4G2, Canada. manu.rangachari@crchudequebec.ulaval.ca. ^[10]