换一批Irinotecan and temozolomide in combination with dasatinib and rapamycin versus irinotecan and temozolomide for patients with relapsed or refractory neuroblastoma (RIST-rNB-2011): a multicentre, open-label, randomised, controlled, phase 2 trial.
第一作者：
Selim,Corbacioglu
第一单位：
University Medical Center Regensburg, Regensburg, Germany; Department of Pediatric Hematology, Oncology, and Stem Cell Transplantation,University Medical Center Regensburg, Regensburg, Germany. Electronic address: selim.corbacioglu@mac.com.
作者：
Selim,Corbacioglu [1]
;
Holger,Lode [2]
;
Susanne,Ellinger [3]
;
Florian,Zeman [3]
;
Meinolf,Suttorp [4]
;
Gabriele,Escherich [5]
;
Konrad,Bochennek [6]
;
Bernd,Gruhn [7]
;
Peter,Lang [8]
;
Marius,Rohde [9]
;
Klaus Michael,Debatin [10]
;
Daniel,Steinbach [10]
;
Andreas,Beilken [11]
;
Ruth,Ladenstein [12]
;
Rainer,Spachtholz [3]
;
Peter,Heiss [3]
;
Dirk,Hellwig [3]
;
Anja,Tröger [3]
;
Michael,Koller [3]
;
Karin,Menhart [3]
;
Markus J,Riemenschneider [3]
;
Saida,Zoubaa [3]
;
Silke,Kietz [3]
;
Marcus,Jakob [3]
;
Gunhild,Sommer [3]
;
Tilman,Heise [3]
;
Patrick,Hundsdörfer [13]
;
Ingrid,Kühnle [14]
;
Dagmar,Dilloo [15]
;
Stefan,Schönberger [16]
;
Georg,Schwabe [17]
;
Irene,von Luettichau [18]
;
Norbert,Graf [19]
;
Paul-Gerhardt,Schlegel [20]
;
Michael,Frühwald [21]
;
Norbert,Jorch [22]
;
Michael,Paulussen [23]
;
Dominik T,Schneider [24]
;
Markus,Metzler [25]
;
Alfred,Leipold [26]
;
Michaela,Nathrath [27]
;
Thomas,Imschweiler [28]
;
Holger,Christiansen [29]
;
Irene,Schmid [30]
;
Roman,Crazzolara [31]
;
Naghmeh,Niktoreh [16]
;
Gunnar,Cario [32]
;
Joerg,Faber [33]
;
Martin,Demmert [34]
;
Florian,Babor [35]
;
Birgit,Fröhlich [36]
;
Stefan,Bielack [37]
;
Toralf,Bernig [38]
;
Johann,Greil [39]
;
Angelika,Eggert [40]
;
Thorsten,Simon [41]
;
Juergen,Foell [3]
作者单位：
University Medical Center Regensburg, Regensburg, Germany; Department of Pediatric Hematology, Oncology, and Stem Cell Transplantation,University Medical Center Regensburg, Regensburg, Germany. Electronic address: selim.corbacioglu@mac.com.
[1]
University Medicine Greifswald, Greifswald, Germany.
[2]
University Medical Center Regensburg, Regensburg, Germany.
[3]
Medical Faculty, Technical University Dresden, Dresden, Germany.
[4]
University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
[5]
University Medical Center Frankfurt, Frankfurt am Main, Germany.
[6]
University Medical Center Jena, Jena, Germany.
[7]
University Medical Center Tuebingen, Tuebingen, Germany.
[8]
University Medical Center Giessen, Giessen, Germany.
[9]
University Medical Center Ulm, Ulm, Germany.
[10]
University Medical Center Hannover, Hannover, Germany.
[11]
St Anna Children's Cancer Research Institute, University Medical Center, Vienna, Austria.
[12]
Helios Klinikum Berlin-Buch, Berlin, Germany.
[13]
University Medical Center Göttingen, Göttingen, Germany.
[14]
University Medical Center Bonn, Bonn, Germany.
[15]
University Medical Center Essen, Essen, Germany.
[16]
Carl-Thieme Clinic Cottbus, Cottbus, Germany.
[17]
Technical University of Munich, Munich, Germany.
[18]
Saarland University, Homburg, Homburg, Germany.
[19]
University Medical Center Würzburg, Würzburg, Germany.
[20]
University Medical Center Augsburg, Augsburg, Germany.
[21]
University Medical Center Bielefeld, Bielefeld, Germany.
[22]
University Medical Center Witten/Herdecke, Datteln, Germany.
[23]
University Medical Center Witten/Herdecke, Dortmund, Germany.
[24]
University Medical Center Erlangen, Erlangen, Germany.
[25]
Medical Center Karlsruhe, Karlsruhe, Germany.
[26]
Klinikum Kassel, Kassel, Germany.
[27]
Helios Hospital Krefeld, Krefeld, Germany.
[28]
University Medical Center Leipzig, Leipzig, Germany.
[29]
Ludwig Maximilians University Munich, Munich, Germany.
[30]
University Medical Center Innsbruck, Innsbruck, Austria.
[31]
University Medical Center Kiel, Kiel, Germany.
[32]
University Medical Center Mainz, Mainz, Germany.
[33]
University Medical Center Lübeck, Lübeck, Germany.
[34]
University Medical Center Düsseldorf, Düsseldorf, Germany.
[35]
University Medical Center Muenster, Muenster, Germany.
[36]
University Medical Center Stuttgart, Stuttgart, Germany.
[37]
University Medical Center Halle, Halle, Germany.
[38]
University Medical Center Heidelberg, Heidelberg, Germany.
[39]
Charité, University Medical Center Berlin, Berlin, Germany.
[40]
University Medical Center Cologne, Cologne, Germany.
[41]
医学主题词
人类(Humans);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);男(雄)性(Male);女(雌)性(Female);神经母细胞瘤(Neuroblastoma);儿童, 学龄前(Child, Preschool);儿童(Child);青少年(Adolescent);肿瘤复发, 局部(Neoplasm Recurrence, Local);婴儿(Infant);成年人(Adult);西罗莫司(Sirolimus);青年人(Young Adult);德国(Germany);抗药性, 肿瘤(Drug Resistance, Neoplasm)
DOI
10.1016/S1470-2045(24)00202-X
PMID
38936379
发布时间
2026-03-25
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The Lancet. Oncology
The Lancet. Oncology
922-932页
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