首页> Oncoimmunology> Modulation of blood T cell polyfunctionality and HVEM/BTLA expression are critical determinants of clinical outcome in anti-PD1-treated metastatic melanoma patients.

Modulation of blood T cell polyfunctionality and HVEM/BTLA expression are critical determinants of clinical outcome in anti-PD1-treated metastatic melanoma patients.

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第一作者： Stéphane,Dalle

第一单位： Department of Dermatology, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon 1 University, Lyon, France.;Cancer Research Center of Lyon, INSERM 1052 - CNRS 5286, Centre Léon Bérard, Université de Lyon, Université Claude Bernard Lyon 1, Lyon, France.

作者： Stéphane,Dalle ^[1] ; Estelle,Verronese ^[2] ; Axelle,N'Kodia ^[2] ; Christine,Bardin ^[2] ; Céline,Rodriguez ^[3] ; Thibault,Andrieu ^[3] ; Anais,Eberhardt ^[1] ; Gabriel,Chemin ^[4] ; Uzma,Hasan ^[2] ; Myrtille,Le-Bouar ^[5] ; Julie,Caramel ^[4] ; Mona,Amini-Adle ^[5] ; Nathalie,Bendriss-Vermare ^[3] ; Bertrand,Dubois ^[3] ; Christophe,Caux ^[3] ; Christine,Ménétrier-Caux ^[3]

作者单位： Department of Dermatology, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon 1 University, Lyon, France.;Cancer Research Center of Lyon, INSERM 1052 - CNRS 5286, Centre Léon Bérard, Université de Lyon, Université Claude Bernard Lyon 1, Lyon, France. ^[1] Lyon Immunotherapy for Cancer Laboratory (LICL), Centre Léon Bérard, Lyon, France. ^[2] Cancer Research Center of Lyon, INSERM 1052 - CNRS 5286, Centre Léon Bérard, Université de Lyon, Université Claude Bernard Lyon 1, Lyon, France.;Lyon Immunotherapy for Cancer Laboratory (LICL), Centre Léon Bérard, Lyon, France. ^[3] Cancer Research Center of Lyon, INSERM 1052 - CNRS 5286, Centre Léon Bérard, Université de Lyon, Université Claude Bernard Lyon 1, Lyon, France. ^[4] Department of Dermatology, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon 1 University, Lyon, France. ^[5]

关键词 Advanced melanoma HVEM T cell polyfunctionality anti-PD1 biomarkers of response blood immuno-monitoring