Cytokines drive the formation of memory-like NK cell subsets via epigenetic rewiring and transcriptional regulation.

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第一作者： Jennifer A,Foltz

第一单位： Washington University School of Medicine, Saint Louis, MO, USA.

作者： Jennifer A,Foltz ^[1] ; Jennifer,Tran ^[1] ; Pamela,Wong ^[1] ; Changxu,Fan ^[2] ; Evelyn,Schmidt ^[1] ; Bryan,Fisk ^[1] ; Michelle,Becker-Hapak ^[1] ; David A,Russler-Germain ^[1] ; Jeanette,Johnson ^[3] ; Nancy D,Marin ^[1] ; Celia C,Cubitt ^[1] ; Patrick,Pence ^[1] ; Joseph,Rueve ^[1] ; Sushanth,Pureti ^[1] ; Kimberly,Hwang ^[1] ; Feng,Gao ^[4] ; Alice Y,Zhou ^[1] ; Mark,Foster ^[1] ; Timothy,Schappe ^[1] ; Lynne,Marsala ^[1] ; Melissa M,Berrien-Elliott ^[1] ; Amanda F,Cashen ^[1] ; Jeffrey J,Bednarski ^[1] ; Elana,Fertig ^[3] ; Obi L,Griffith ^[5] ; Malachi,Griffith ^[5] ; Ting,Wang ^[2] ; Allegra A,Petti ^[6] ; Todd A,Fehniger ^[4]

作者单位： Washington University School of Medicine, Saint Louis, MO, USA. ^[1] Washington University School of Medicine, Saint Louis, MO, USA.;McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA. ^[2] Johns Hopkins University, Baltimore, MD, USA. ^[3] Washington University School of Medicine, Saint Louis, MO, USA.;Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO, USA. ^[4] Washington University School of Medicine, Saint Louis, MO, USA.;McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA.;Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO, USA. ^[5] Washington University School of Medicine, Saint Louis, MO, USA.;Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. ^[6]

主题词人类(Humans);杀伤细胞, 天然(Killer Cells, Natural);后成说, 遗传(Epigenesis, Genetic);免疫记忆(Immunologic Memory);细胞因子类(Cytokines);基因表达调控(Gene Expression Regulation);细胞分化(Cell Differentiation);白细胞介素15(Interleukin-15)

DOI 10.1126/sciimmunol.adk4893

PMID 38941480

发布时间 2025-02-06

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Science immunology

2024年9卷96期

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Cytokines drive the formation of memory-like NK cell subsets via epigenetic rewiring and transcriptional regulation.

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Cytokines drive the formation of memory-like NK cell subsets via epigenetic rewiring and transcriptional regulation.

Science immunology

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Science immunology

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