Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer.
第一作者:
Linda,Bojmar
第一单位:
Departments of Pediatrics and Cell and Developmental Biology, Children's Cancer and Blood Foundation Laboratories, Drukier Institute for Children's Health, Meyer Cancer Center Weill Cornell Medicine, New York, NY, USA.;Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
作者:
Linda,Bojmar [1]
;
Constantinos P,Zambirinis [2]
;
Jonathan M,Hernandez [3]
;
Jayasree,Chakraborty [4]
;
Lee,Shaashua [5]
;
Junbum,Kim [6]
;
Kofi Ennu,Johnson [5]
;
Samer,Hanna [5]
;
Gokce,Askan [7]
;
Jonas,Burman [1]
;
Hiranmayi,Ravichandran [8]
;
Jian,Zheng [9]
;
Joshua S,Jolissaint [10]
;
Rami,Srouji [10]
;
Yi,Song [9]
;
Ankur,Choubey [9]
;
Han Sang,Kim [5]
;
Michele,Cioffi [5]
;
Elke,van Beek [9]
;
Carlie,Sigel [7]
;
Jose,Jessurun [11]
;
Paulina,Velasco Riestra [12]
;
Hakon,Blomstrand [13]
;
Carolin,Jönsson [12]
;
Anette,Jönsson [12]
;
Pernille,Lauritzen [5]
;
Weston,Buehring [5]
;
Yonathan,Ararso [5]
;
Dylanne,Hernandez [5]
;
Jessica P,Vinagolu-Baur [5]
;
Madison,Friedman [5]
;
Caroline,Glidden [5]
;
Laetitia,Firmenich [5]
;
Grace,Lieberman [5]
;
Dianna L,Mejia [5]
;
Naaz,Nasar [9]
;
Anders P,Mutvei [14]
;
Doru M,Paul [15]
;
Yaron,Bram [16]
;
Bruno,Costa-Silva [5]
;
Olca,Basturk [7]
;
Nancy,Boudreau [5]
;
Haiying,Zhang [5]
;
Irina R,Matei [5]
;
Ayuko,Hoshino [5]
;
David,Kelsen [17]
;
Irit,Sagi [18]
;
Avigdor,Scherz [19]
;
Ruth,Scherz-Shouval [20]
;
Yosef,Yarden [18]
;
Moshe,Oren [21]
;
Mikala,Egeblad [22]
;
Jason S,Lewis [23]
;
Kayvan,Keshari [24]
;
Paul M,Grandgenett [25]
;
Michael A,Hollingsworth [25]
;
Vinagolu K,Rajasekhar [26]
;
John H,Healey [26]
;
Bergthor,Björnsson [12]
;
Diane M,Simeone [27]
;
David A,Tuveson [22]
;
Christine A,Iacobuzio-Donahue [28]
;
Jaqueline,Bromberg [29]
;
C Theresa,Vincent [30]
;
Eileen M,O'Reilly [31]
;
Ronald P,DeMatteo [9]
;
Vinod P,Balachandran [32]
;
Michael I,D'Angelica [4]
;
T Peter,Kingham [4]
;
Peter J,Allen [9]
;
Amber L,Simpson [9]
;
Olivier,Elemento [8]
;
Per,Sandström [12]
;
Robert E,Schwartz [33]
;
William R,Jarnagin [4]
;
David,Lyden [34]
作者单位:
Departments of Pediatrics and Cell and Developmental Biology, Children's Cancer and Blood Foundation Laboratories, Drukier Institute for Children's Health, Meyer Cancer Center Weill Cornell Medicine, New York, NY, USA.;Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
[1]
Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.;Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.;Division of Surgical Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA.
[2]
Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.;Thoracic and Gastrointestinal Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
[3]
Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.;David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
[4]
Departments of Pediatrics and Cell and Developmental Biology, Children's Cancer and Blood Foundation Laboratories, Drukier Institute for Children's Health, Meyer Cancer Center Weill Cornell Medicine, New York, NY, USA.
[5]
Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.
[6]
David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.;Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
[7]
Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.;Caryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.
[8]
Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
[9]
Departments of Pediatrics and Cell and Developmental Biology, Children's Cancer and Blood Foundation Laboratories, Drukier Institute for Children's Health, Meyer Cancer Center Weill Cornell Medicine, New York, NY, USA.;Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
[10]
Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
[11]
Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
[12]
Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.;Department of Clinical Pathology, Linköping University, Linköping, Sweden.
[13]
Department of Laboratory Medicine, Division of Pathology, Karolinska Institutet, Stockholm, Sweden.
[14]
Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
[15]
Division of Gastroenterology & Hepatology, Weill Cornell Medicine, New York, NY, USA.
[16]
David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.;Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
[17]
Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.
[18]
Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, Israel.
[19]
Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.
[20]
Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
[21]
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
[22]
Radiology and Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.;Weill Cornell Medical College, New York, NY, USA.
[23]
David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.;Radiology and Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
[24]
Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA.
[25]
Orthopedic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
[26]
Perlmutter Cancer Center, New York University Langone Health, New York, NY, USA.
[27]
David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.;Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.;Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
[28]
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.;Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
[29]
Department of Laboratory Medicine, Division of Pathology, Karolinska Institutet, Stockholm, Sweden.;Department of Microbiology, New York University Grossman School of Medicine, New York, NY, USA.
[30]
David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.;Division of Hematology and Medical Oncology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.;Weill Cornell Medical College, New York, NY, USA.
[31]
Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.;David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA.;Immuno-Oncology Service, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
[32]
Division of Gastroenterology & Hepatology, Weill Cornell Medicine, New York, NY, USA.;Department of Biomedical Engineering, Cornell University, Ithaca, NY, USA.
[33]
Departments of Pediatrics and Cell and Developmental Biology, Children's Cancer and Blood Foundation Laboratories, Drukier Institute for Children's Health, Meyer Cancer Center Weill Cornell Medicine, New York, NY, USA. dcl2001@med.cornell.edu.;David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA. dcl2001@med.cornell.edu.
[34]
主题词
人类(Humans);胰腺肿瘤(Pancreatic Neoplasms);肝肿瘤(Liver Neoplasms);男(雄)性(Male);女(雌)性(Female);中年人(Middle Aged);老年人(Aged);肝(Liver);活组织检查(Biopsy);肿瘤分期(Neoplasm Staging);胰腺切除术(Pancreatectomy);预后(Prognosis)
DOI
10.1038/s41591-024-03075-7
PMID
38942992
发布时间
2025-07-21
- 浏览0
Nature medicine
Nature medicine
2170-2180页
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