The LIDPAD Mouse Model Captures the Multisystem Interactions and Extrahepatic Complications in MASLD.
作者:
Zun Siong,Low [1]
;
Damien,Chua [1]
;
Hong Sheng,Cheng [1]
;
Rachel,Tee [1]
;
Wei Ren,Tan [1]
;
Christopher,Ball [2]
;
Norliza Binte Esmail,Sahib [1]
;
Ser Sue,Ng [1]
;
Jing,Qu [3]
;
Yingzi,Liu [4]
;
Haiyu,Hong [5]
;
Chaonong,Cai [5]
;
Nandini Chilagondanahalli Lakshmi,Rao [6]
;
Aileen,Wee [7]
;
Mark Dhinesh,Muthiah [8]
;
Zoë,Bichler [1]
;
Barbara,Mickelson [9]
;
Mei Suen,Kong [1]
;
Vanessa Shiyun,Tay [1]
;
Zhuang,Yan [1]
;
Jiapeng,Chen [1]
;
Aik Seng,Ng [10]
;
Yun Sheng,Yip [1]
;
Marcus Ivan Gerard,Vos [1]
;
Nicole Ashley,Tan [11]
;
Dao Liang,Lim [11]
;
Debbie Xiu En,Lim [1]
;
Manesh,Chittezhath [1]
;
Jadegoud,Yaligar [12]
;
Sanjay Kumar,Verma [2]
;
Harish,Poptani [13]
;
Xue Li,Guan [1]
;
Sambasivam Sendhil,Velan [14]
;
Yusuf,Ali [15]
;
Liang,Li [16]
;
Nguan Soon,Tan [17]
;
Walter,Wahli [18]
作者单位:
Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Clinical Sciences Building, 11 Mandalay Road, Singapore, 308232, Singapore.
[1]
Metabolic Imaging Group, Institute of Bioengineering and Bioimaging, Agency for Science Technology and Research (A*STAR), 11 Biopolis Way, Singapore, 138667, Singapore.
[2]
Department of Pathogen Biology, Shenzhen Center for Disease Control and Prevention, Shenzhen, 518055, China.
[3]
Intervention and Cell Therapy Center, Peking University Shenzhen Hospital, Shenzhen, 518036, China.
[4]
Department of Otolaryngology Head and Neck Surgery, The Fifth Affiliated Hospital of Sun Yat-sen University, 52 Mei Hua East Road, Zhuhai, 519000, China.
[5]
Department of Pathology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore.
[6]
Department of Pathology, National University Hospital, 5 Lower Kent Ridge Rd, Singapore, 119074, Singapore.
[7]
Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597, Singapore.;Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore, 119074, Singapore.;National University Centre for Organ Transplantation, National University Health System, Singapore, 119074, Singapore.
[8]
ENVIGO, Madison, WI, 53713, USA.
[9]
Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, UK.
[10]
School of Biological Sciences, Nanyang Technological University Singapore, 60 Nanyang Drive, Singapore, 637551, Singapore.
[11]
Metabolic Imaging Group, Institute of Bioengineering and Bioimaging, Agency for Science Technology and Research (A*STAR), 11 Biopolis Way, Singapore, 138667, Singapore.;Singapore Institute for Clinical Sciences, A*STAR, 30 Medical Drive, Singapore, 117609, Singapore.
[12]
Centre for Preclinical Imaging, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Biosciences Building, Crown Street, Liverpool, L69 7BE, UK.
[13]
Metabolic Imaging Group, Institute of Bioengineering and Bioimaging, Agency for Science Technology and Research (A*STAR), 11 Biopolis Way, Singapore, 138667, Singapore.;Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore, 119074, Singapore.;Singapore Institute for Clinical Sciences, A*STAR, 30 Medical Drive, Singapore, 117609, Singapore.
[14]
Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Clinical Sciences Building, 11 Mandalay Road, Singapore, 308232, Singapore.;Singapore Eye Research Institute (SERI), Singapore General Hospital, Singapore, 168751, Singapore.
[15]
Department of Pharmacology, School of Medicine, Southern University of Science and Technology, Shenzhen, 518055, China.
[16]
Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Clinical Sciences Building, 11 Mandalay Road, Singapore, 308232, Singapore.;School of Biological Sciences, Nanyang Technological University Singapore, 60 Nanyang Drive, Singapore, 637551, Singapore.
[17]
Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Clinical Sciences Building, 11 Mandalay Road, Singapore, 308232, Singapore.;Institut national de recherche pour l'agriculture, l'alimentation et l'environnement (INRAE), Toxalim (Research Centre in Food Toxicology), 180 Chemin de Tournefeuille, Toulouse, 1331, France.;Center for Integrative Genomics, Université de Lausanne, Le Génopode, Lausanne, 1015, Switzerland.
[18]
主题词
动物(Animals);小鼠(Mice);疾病模型, 动物(Disease Models, Animal);脂肪肝(Fatty Liver);疾病恶化(Disease Progression);小鼠, 近交C57BL(Mice, Inbred C57BL);人类(Humans);膳食(Diet);肝(Liver)
DOI
10.1002/advs.202404326
PMID
38952069
发布时间
2024-09-28
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Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
2024年11卷35期
e2404326页
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