GSDME-mediated pyroptosis promotes anti-tumor immunity of neoadjuvant chemotherapy in breast cancer.

导出 OA

翻译打印收藏纠错

作者： Changfang,Fu ^[1] ; Wenbo,Ji ^[2] ; Qianwen,Cui ^[3] ; Anling,Chen ^[3] ; Haiyan,Weng ^[4] ; Nannan,Lu ^[5] ; Wulin,Yang ^[6]

作者单位： Department of Pharmacy, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, Anhui, China.;Anhui Provincial Key Laboratory of Precision Pharmaceutical Preparations and Clinical Pharmacy, Hefei, 230001, Anhui, China. ^[1] Clinical Pharmacy Department, Anhui Provincial Children's Hospital, Hefei, 230000, Anhui, China. ^[2] Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China. ^[3] Department of Pathology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, Anhui, China. ^[4] Department of Oncology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, Anhui, China. lnn279@ustc.edu.cn. ^[5] Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China. yangw@cmpt.ac.cn.;Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China. yangw@cmpt.ac.cn. ^[6]

关键词 Breast cancer Immunogenic cell death Neoadjuvant chemotherapy Pathological complete response Pyroptosis