首页> Cellular & molecular biology letters> Impairment of α-tubulin and F-actin interactions of GJB3 induces aneuploidy in urothelial cells and promotes bladder cancer cell invasion.

Impairment of α-tubulin and F-actin interactions of GJB3 induces aneuploidy in urothelial cells and promotes bladder cancer cell invasion.

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第一作者： Junnan,Liu

第一单位： Department of Urology, Ulm University Hospital, Helmholtzstr. 10, 89081, Ulm, Germany.;Department of Urology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.

作者： Junnan,Liu ^[1] ; Xue,Wang ^[2] ; Wencheng,Jiang ^[3] ; Anca,Azoitei ^[3] ; Tim,Eiseler ^[4] ; Markus,Eckstein ^[5] ; Arndt,Hartmann ^[5] ; Stephan,Stilgenbauer ^[6] ; Mohamed,Elati ^[7] ; Meike,Hohwieler ^[8] ; Alexander,Kleger ^[8] ; Axel,John ^[3] ; Felix,Wezel ^[3] ; Friedemann,Zengerling ^[3] ; Christian,Bolenz ^[3] ; Cagatay,Günes ^[9]

作者单位： Department of Urology, Ulm University Hospital, Helmholtzstr. 10, 89081, Ulm, Germany.;Department of Urology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA. ^[1] Department of Urology, Ulm University Hospital, Helmholtzstr. 10, 89081, Ulm, Germany.;Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine and Science, Rochester, MN, USA. ^[2] Department of Urology, Ulm University Hospital, Helmholtzstr. 10, 89081, Ulm, Germany. ^[3] Department of Internal Medicine I, Ulm University Hospital, Ulm, Germany. ^[4] Institute of Pathology, Friedrich-Alexander University, Erlangen, Germany. ^[5] Department of Internal Medicine III, Ulm University, Ulm, Germany. ^[6] CANTHER, ONCOLille Institute, University of Lille, CNRS, UMR 1277, Inserm U9020, 59045, Lille Cedex, France. ^[7] Institute of Molecular Oncology and Stem Cell Biology, Ulm University Hospital, Ulm, Germany. ^[8] Department of Urology, Ulm University Hospital, Helmholtzstr. 10, 89081, Ulm, Germany. Cagatay.guenes@uniklinik-ulm.de. ^[9]

关键词 Chromosomal imbalance Invadopodia MIBC Metastasis Spindle orientation