β-Mangostin targets and suppresses glioma via STING activation and tumor-associated microglia polarization.

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作者： Yimin,Yang ^[1] ; Xuling,Luo ^[1] ; Yaling,Wang ^[2] ; Aibo,Xu ^[2] ; Lina,Peng ^[2] ; Xiaoting,Zhang ^[1] ; Zhen,Wang ^[3] ; Youmin,Ying ^[4] ; Kaiqiang,Li ^[5]

作者单位： College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China. ^[1] Center for Laboratory Medicine, Allergy center, Department of Transfusion medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang 310014, China. ^[2] Center for Laboratory Medicine, Allergy center, Department of Transfusion medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang 310014, China; Key Laboratory of Biomarkers and In Vitro Diagnosis Translation of Zhejiang Province, Hangzhou, Zhejiang 310063, China. Electronic address: wangzhen@hmc.edu.cn. ^[3] College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China. Electronic address: ymying@zjut.edu.cn. ^[4] Center for Laboratory Medicine, Allergy center, Department of Transfusion medicine, Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College, Hangzhou, Zhejiang 310014, China; Key Laboratory of Biomarkers and In Vitro Diagnosis Translation of Zhejiang Province, Hangzhou, Zhejiang 310063, China. Electronic address: likaiqiang@hmc.edu.cn. ^[5]

关键词 Anti-PD-1 antibody Biosafety Immunosuppressive microenvironment Mangosteen Stimulator of interferon genes Xanthone