Sevoflurane impedes neuropathic pain by maintaining endoplasmic reticulum stress and oxidative stress homeostasis through inhibiting the activation of the PLCγ/CaMKII/IP3R signaling pathway.
作者:
主题词
动物(Animals);神经痛(Neuralgia);信号传导(Signal Transduction);氧化性应激(Oxidative Stress);钙-钙调素依赖性蛋白激酶2型(Calcium-Calmodulin-Dependent Protein Kinase Type 2);小鼠(Mice);磷脂酶Cγ(Phospholipase C gamma);肌醇1,4,5-三磷酸受体(Inositol 1,4,5-Trisphosphate Receptors);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);脊髓(Spinal Cord);内环境稳定(Homeostasis);疾病模型, 动物(Disease Models, Animal);坐骨神经(Sciatic Nerve)
DOI
10.18632/aging.206001
PMID
38975935
发布时间
2024-08-30
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Aging
11062-11071页
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