The role of platelet desialylation as a biomarker in primary immune thrombocytopenia: mechanisms and therapeutic perspectives.

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第一作者： Qianhui,Zhang

第一单位： State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

作者： Qianhui,Zhang ^[1] ; Miao,Huang ^[2] ; Elizabeth Rosalind,Thomas ^[3] ; Lu,Wang ^[1] ; Jia,Liu ^[1] ; Xiang,Li ^[4] ; Jiesi,Luo ^[4] ; Wenjun,Zou ^[1] ; Jianming,Wu ^[5]

作者单位： State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu, China. ^[1] State Key Laboratory of Southwestern Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu, China.;School of Basic Medical Sciences, Southwest Medical University, Luzhou, China. ^[2] Department of Microbiology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, India. ^[3] School of Basic Medical Sciences, Southwest Medical University, Luzhou, China. ^[4] School of Basic Medical Sciences, Southwest Medical University, Luzhou, China.;Education Ministry Key Laboratory of Medical Electrophysiology, Medical Key Laboratory for Drug Discovery and Druggability Evaluation of Sichuan Province, Luzhou Key Laboratory of Activity Screening and Druggability Evaluation for Chinese Materia Medica, Luzhou, China. ^[5]

关键词 apoptosis pathogenesis platelets primary immune thrombocytopenia sialic acid

主题词人类(Humans);紫癜, 血小板减少性, 特发性(Purpura, Thrombocytopenic, Idiopathic);血小板(Blood Platelets);动物(Animals);自身抗体(Autoantibodies);糖基化(Glycosylation)

DOI 10.3389/fimmu.2024.1409461

PMID 38979425

发布时间 2024-07-10

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