Synthesis and mutagenic risk of avanafil's potential genotoxic impurities.

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作者： Yunkai,Sun ^[1] ; Xiaoxia,Wu ^[2] ; Pei,Zuo ^[2] ; Zhao,Liu ^[3] ; Xuepei,Miao ^[3] ; Jian,Liu ^[3] ; Hairuo,Wen ^[1]

作者单位： School of Chemical Engineering and Materials, Changzhou Institute of Technology Changzhou 213022 China sunyunkai1983@163.com. ^[1] School of Chemistry and Chemical Engineering, University of South China Hengyang 421001 China. ^[2] Harvest Pharmaceutical Co., Ltd Changsha 410000 China liuz@harvest-pharm.com. ^[3] National Center for Safety Evaluation of Drugs, National Institutes for Food and Drug Control, Key Laboratory of Beijing for Nonclinical Safety Evaluation Research of Drugs Beijing 100176 P. R. China wenhairuo@nifdc.org.cn. ^[4]

DOI 10.1039/d4ra02345e

PMID 38979469

发布时间 2024-07-10

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RSC advances

2024年14卷30期

21432-21438页

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Synthesis and mutagenic risk of avanafil's potential genotoxic impurities.

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Synthesis and mutagenic risk of avanafil's potential genotoxic impurities.

RSC advances

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RSC advances

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