Modular Prodrug-Engineered Oxygen Nano-Tank With Outstanding Nanoassembly Performance, High Oxygen Loading, and Closed-Loop Tumor Hypoxia Relief.

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第一作者： Fujun,Yang

第一单位： Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, P. R. China.;Joint International Research Laboratory of Intelligent Drug Delivery Systems, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, P. R. China.

作者： Fujun,Yang ^[1] ; Shumeng,Li ^[2] ; Qingyu,Ji ^[1] ; Hongyuan,Zhang ^[1] ; Mingyang,Zhou ^[3] ; Yuequan,Wang ^[1] ; Shenwu,Zhang ^[1] ; Jin,Sun ^[1] ; Zhonggui,He ^[1] ; Cong,Luo ^[1]

作者单位： Department of Pharmaceutics, Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, 110016, P. R. China.;Joint International Research Laboratory of Intelligent Drug Delivery Systems, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016, P. R. China. ^[1] Department of Pharmaceutical Analysis, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, P. R. China. ^[2] Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, 19104-6323, USA. ^[3]

关键词 carrier‐free nanoassembly fluorination prodrug hypoxia alleviation oxygen supply/consumption modulation photodynamic therapy

主题词药物前体(Prodrugs);小鼠(Mice);动物(Animals);氧(Oxygen);人类(Humans);细胞系, 肿瘤(Cell Line, Tumor);光化学疗法(Photochemotherapy);疾病模型, 动物(Disease Models, Animal);叶绿素(Chlorophyll);小鼠, 裸(Mice, Nude);纳米技术(Nanotechnology)

DOI 10.1002/advs.202405583

PMID 38984484

发布时间 2024-09-28

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

2024年11卷34期

e2405583页

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Modular Prodrug-Engineered Oxygen Nano-Tank With Outstanding Nanoassembly Performance, High Oxygen Loading, and Closed-Loop Tumor Hypoxia Relief.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Modular Prodrug-Engineered Oxygen Nano-Tank With Outstanding Nanoassembly Performance, High Oxygen Loading, and Closed-Loop Tumor Hypoxia Relief.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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