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Physiological Adaptations to Progressive Endurance Exercise Training in Adult and Aged Rats: Insights from the Molecular Transducers of Physical Activity Consortium (MoTrPAC).

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第一作者： Simon,Schenk

第一单位： Department of Orthopaedic Surgery, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA.

作者： Simon,Schenk ^[1] ; Tyler J,Sagendorf ^[2] ; Gina M,Many ^[2] ; Ana K,Lira ^[3] ; Luis G O,de Sousa ^[4] ; Dam,Bae ^[3] ; Michael,Cicha ^[3] ; Kyle S,Kramer ^[3] ; Michael,Muehlbauer ^[5] ; Andrea L,Hevener ^[6] ; R Scott,Rector ^[7] ; John P,Thyfault ^[8] ; John P,Williams ^[9] ; Laurie J,Goodyear ^[10] ; Karyn A,Esser ^[11] ; Christopher B,Newgard ^[5] ; Sue C,Bodine ^[4] ; MoTrPAC Study Group

作者单位： Department of Orthopaedic Surgery, School of Medicine, University of California San Diego, La Jolla, CA 92093, USA. ^[1] Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA. ^[2] Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA. ^[3] Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.;Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA. ^[4] Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC 27701, USA. ^[5] Division of Endocrinology, Diabetes, and Hypertension, Department of Medicine, University of California, Los Angeles, CA 90095, USA. ^[6] Research Service, Harry S. Truman Memorial Veterans' Medical Center, Columbia, MO 65201, USA.;NextGen Precision Health, University of Missouri, Columbia, MO 65201, USA.;Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, MO 65211, USA.;Division of Gastroenterology and Hepatology, Department of Medicine, University of Missouri, Columbia, MO 65211, USA. ^[7] Department of Cell Biology and Physiology, University of Kansas Medical Center, Kansas City, KS 66160, USA.;KU Diabetes Institute, University of Kansas Medical Center, Kansas City, KS 66160, USA. ^[8] Division of Aging Biology, National Institute on Aging, National Institutes of Health, Bethesda, MD 20898, USA. ^[9] Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA 02215, USA. ^[10] Department of Physiology and Aging, College of Medicine, University of Florida, Gainesville, FL 32610, USA. ^[11]

关键词 aging biorepository body composition citrate synthase maximal oxygen uptake skeletal muscle training treadmill

主题词动物(Animals);男(雄)性(Male);大鼠, 近交F344(Rats, Inbred F344);女(雌)性(Female);身体条件作用, 动物(Physical Conditioning, Animal);适应, 生理学(Adaptation, Physiological);大鼠(Rats);衰老(Aging);身体耐力(Physical Endurance);肌, 骨骼(Muscle, Skeletal)

DOI 10.1093/function/zqae014

PMID 38984994

发布时间 2025-10-21

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Function (Oxford, England)

2024年5卷4期

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Physiological Adaptations to Progressive Endurance Exercise Training in Adult and Aged Rats: Insights from the Molecular Transducers of Physical Activity Consortium (MoTrPAC).

Function (Oxford, England)

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Physiological Adaptations to Progressive Endurance Exercise Training in Adult and Aged Rats: Insights from the Molecular Transducers of Physical Activity Consortium (MoTrPAC).

Function (Oxford, England)

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Function (Oxford, England)

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