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Targeting HTR2B suppresses nonfunctioning pituitary adenoma growth and sensitizes cabergoline treatment via inhibiting Gαq/PLC/PKCγ/STAT3 axis.

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作者: Shaojian,Lin [1] ; Liangbo,Wang [2] ; Changxi,Han [1] ; Yuting,Dai [3] ; Changsheng,Li [1] ; Yanting,Liu [1] ; Bo,Zhang [1] ; Ning,Huang [2] ; Anke,Zhang [4] ; Tao,Zhang [2] ; Yu,Wang [5] ; Jing,Xie [6] ; Hao,Tang [1] ; Yijun,Cheng [1] ; Hong,Yao [7] ; Meiqing,Lou [8] ; Li,Xue [8] ; Zhe Bao,Wu
作者单位: Department of Neurosurgery, Center of Pituitary Tumor, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [1] Department of Neurosurgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. [2] Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [3] Department of Neurosurgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China. [4] Department of Neurosurgery, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [5] Department of Pathology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [6] Department of Neurosurgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [7] Department of Neurosurgery, Center of Pituitary Tumor, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.;Department of Neurosurgery, Center for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [8]
DOI 10.1093/neuonc/noae130
PMID 38989697
发布时间 2024-11-06
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