The Discovery of Novel α<sub>2a</sub> Adrenergic Receptor Agonists Only Coupling to Gαi/O Proteins by Virtual Screening.
第一作者:
Peilan,Zhou
第一单位:
State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Key Laboratory of Neuropsychopharmacology, Beijing Institute of Pharmacology and Toxicology, 27th Taiping Road, Beijing 100850, China.
作者:
医学主题词
人类(Humans);动物(Animals);HEK293细胞(HEK293 Cells);受体, 肾上腺素能α2(Receptors, Adrenergic, alpha-2);肾上腺素能α-2受体激动剂(Adrenergic alpha-2 Receptor Agonists);小鼠(Mice);GTP结合蛋白质α亚单位, Gi-Go(GTP-Binding Protein alpha Subunits, Gi-Go);环AMP(Cyclic AMP);男(雄)性(Male);蛋白质结合(Protein Binding)
DOI
10.3390/ijms25137233
PMID
39000340
发布时间
2024-08-09
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