The Antimicrobial Activity of Human Defensins at Physiological Non-Permeabilizing Concentrations Is Caused by the Inhibition of the Plasma Membrane H<sup>+</sup>-ATPases.

导出 OA

翻译打印收藏纠错

第一作者： María T,Andrés

第一单位： Laboratory of Oral Microbiology (LMO), University Clinic of Dentistry (CLUO), University of Oviedo, 33006 Oviedo, Asturias, Spain.;Health Research Institute of the Principality of Asturias (ISPA), 33011 Oviedo, Spain.;SamerLabs SL, Asturias Technology Park, 33428 Llanera, Spain.

作者： María T,Andrés ^[1] ; Patricia,Fierro ^[2] ; Victoria,Antuña ^[3] ; José F,Fierro ^[4]

作者单位： Laboratory of Oral Microbiology (LMO), University Clinic of Dentistry (CLUO), University of Oviedo, 33006 Oviedo, Asturias, Spain.;Health Research Institute of the Principality of Asturias (ISPA), 33011 Oviedo, Spain.;SamerLabs SL, Asturias Technology Park, 33428 Llanera, Spain. ^[1] Laboratory of Oral Microbiology (LMO), University Clinic of Dentistry (CLUO), University of Oviedo, 33006 Oviedo, Asturias, Spain.;Primary Care Emergency Service, Cantabrian Health Service, 39000 Santander, Spain. ^[2] Laboratory of Oral Microbiology (LMO), University Clinic of Dentistry (CLUO), University of Oviedo, 33006 Oviedo, Asturias, Spain. ^[3] Laboratory of Oral Microbiology (LMO), University Clinic of Dentistry (CLUO), University of Oviedo, 33006 Oviedo, Asturias, Spain.;Health Research Institute of the Principality of Asturias (ISPA), 33011 Oviedo, Spain.;Deparment of Functional Biology (Microbiology), Faculty of Medicine, University of Oviedo, 33006 Oviedo, Spain. ^[4]

关键词 H+-ATPase HNP-1 HNP-4 Pma1p antimicrobial mechanism of action antimicrobial peptide gamma-core motif hBD-2 hBD-3 human defensin