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Discovery and evolution of berberine analogues as anti-Helicobacter pylori agents with multi-target mechanisms.

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作者: Xin,Zhang [1] ; Genzhu,Wang [2] ; Wenhua,Kuang [3] ; Liting,Xu [3] ; Yuting,He [3] ; Lirun,Zhou [3] ; Ying,Zhang [3] ; Ruixing,Chen [3] ; Huiying,Li [4] ; Tianyun,Fan [5] ; Yali,Song [6] ; Jigang,Wang [7]
作者单位: Department of Clinical Pharmacy, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, 272000, China. [1] Department of Clinical Pharmacy, Electric Power Teaching Hospital, Capital Medical University, Beijing, 100073, China. [2] State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. [3] Dongguan Maternal and Child Health Care Hospital, Postdoctoral Innovation Practice Base of Southern Medical University, Dongguan, Guangdong, 523000, China; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. [4] Dongguan Maternal and Child Health Care Hospital, Postdoctoral Innovation Practice Base of Southern Medical University, Dongguan, Guangdong, 523000, China; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. Electronic address: fty1668@163.com. [5] Dongguan Maternal and Child Health Care Hospital, Postdoctoral Innovation Practice Base of Southern Medical University, Dongguan, Guangdong, 523000, China. Electronic address: syl@smu.edu.cn. [6] Dongguan Maternal and Child Health Care Hospital, Postdoctoral Innovation Practice Base of Southern Medical University, Dongguan, Guangdong, 523000, China; Department of Critical Medicine, Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People's Hospital, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen, Guangdong 518020, China; State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. Electronic address: jgwang@icmm.ac.cn. [7]
DOI 10.1016/j.bioorg.2024.107628
PMID 39018799
发布时间 2024-08-30
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