Biofluid specific protein coronas affect lipid nanoparticle behavior in vitro.

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作者： Demian,van Straten ^[1] ; Helena,Sork ^[2] ; Luuk,van de Schepop ^[3] ; Rowan,Frunt ^[3] ; Kariem,Ezzat ^[4] ; Raymond M,Schiffelers ^[3]

作者单位： CDL Research, University Medical Center Utrecht, Utrecht, the Netherlands. Electronic address: d.vanstraten@umcutrecht.nl. ^[1] Institute of Technology, University of Tartu, 50411 Tartu, Estonia. ^[2] CDL Research, University Medical Center Utrecht, Utrecht, the Netherlands. ^[3] Regain Therapeutics, 141 52 Huddinge, Sweden. ^[4]

关键词 Biofluids Brain Characterization Lipid nanoparticles Protein corona RNA delivery

主题词纳米粒子(Nanoparticles);人类(Humans);脂类(Lipids);脑脊髓液(Cerebrospinal Fluid);脂质体(Liposomes)

DOI 10.1016/j.jconrel.2024.07.044

PMID 39032575

发布时间 2024-09-10

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准确一般字义偏差语意偏离译文作用小提交