A "Dual-Key-and-Lock" MRI Contrast Agent with T<sub>1</sub>-T<sub>2</sub> Switchable Function for Accurate Diagnosis of Tumors.

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作者： Zhongzhong,Lu ^[1] ; Jincong,Yan ^[1] ; Mingsheng,Xu ^[1] ; Jihuan,Liu ^[1] ; Jianxian,Zeng ^[2] ; Yuxin,Ren ^[3] ; Lina,Sun ^[4] ; Ye,Zhang ^[4] ; Yi,Cao ^[4] ; Renjun,Pei ^[1]

作者单位： School of Nano-Tech and Nano-Bionics, University of Science and Technology of China, Hefei 230026, China.;CAS Key Laboratory of Nano-Bio Interface, Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, China. ^[1] Department of Radiology, the First Affiliated Hospital of Soochow University, Suzhou 215006, China. ^[2] Department of Cardiology, the Second Affiliated Hospital of Soochow University, Suzhou 215004, China. ^[3] CAS Key Laboratory of Nano-Bio Interface, Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, China. ^[4]

关键词 T1?T2 switch bioorthogonal click reaction hypoxia weak acidity “dual key-and-lock”

主题词造影剂(Contrast Media);磁共振成像(Magnetic Resonance Imaging);动物(Animals);小鼠(Mice);人类(Humans);肿瘤(Neoplasms);细胞系, 肿瘤(Cell Line, Tumor)

DOI 10.1021/acs.nanolett.4c02669

PMID 39036992

发布时间 2024-07-31

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准确一般字义偏差语意偏离译文作用小提交