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首页> American journal of physiology. Gastrointestinal and liver physiology> Choline-deficient, high-fat diet-induced MASH in Göttingen Minipigs: characterization and effects of a chow reversal period.

Choline-deficient, high-fat diet-induced MASH in Göttingen Minipigs: characterization and effects of a chow reversal period.

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作者： Henning,Hvid ^[1] ; Sara T,Hjuler ^[1] ; Pierre,Bedossa ^[2] ; Dina G,Tiniakos ^[3] ; Ioannis,Kamzolas ^[4] ; Lea M,Harder ^[1] ; Yaxin,Xue ^[1] ; James W,Perfield ^[5] ; Rikke K,Kirk ^[1] ; Markus,Latta ^[1] ; Lars F,Mikkelsen ^[6] ; Henrik D,Pedersen ^[1] ; LITMUS Investigators

作者单位： Research and Early Development, Novo Nordisk A/S, Maaloev, Denmark. ^[1] LIVERPAT, Paris, France. ^[2] Department of Pathology, Aretaieion Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.;Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom. ^[3] Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.;European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, United Kingdom. ^[4] Lilly Research Labs, Eli Lilly and Company, Indianapolis, Indiana, United States. ^[5] Ellegard Göttingen Minipigs A/S, Dalmose, Denmark. ^[6]

关键词 G?ttingen Minipigs MASH MASLD choline-deficient high-fat diet liver

主题词动物(Animals);猪, 雏型(Swine, Miniature);猪(Swine);肝(Liver);疾病模型, 动物(Disease Models, Animal);胆碱缺乏症(Choline Deficiency);脂肪肝(Fatty Liver);男(雄)性(Male);胆碱(Choline);女(雌)性(Female)

DOI 10.1152/ajpgi.00120.2024

PMID 39041677

发布时间 2024-10-18

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American journal of physiology. Gastrointestinal and liver physiology

American journal of physiology. Gastrointestinal and liver physiology

2024年327卷4期

G571-G585页

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American journal of physiology. Gastrointestinal and liver physiology

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American journal of physiology. Gastrointestinal and liver physiology

2024年327卷4期

G571-G585页

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