Targeting the glucocorticoid receptor-CCR8 axis mediated bone marrow T cell sequestration enhances infiltration of anti-tumor T cells in intracranial cancers.
第一作者:
Jia,Zhang
第一单位:
The Third Affiliated Hospital of Soochow University, Institutes for Translational Medicine, State Key Laboratory of Radiation Medicine and Protection, Soochow University Suzhou Medical College, Suzhou, Jiangsu, China.
作者:
主题词
动物(Animals);受体, 糖皮质激素(Receptors, Glucocorticoid);脑肿瘤(Brain Neoplasms);受体, CCR8(Receptors, CCR8);小鼠(Mice);T淋巴细胞(T-Lymphocytes);小鼠, 近交C57BL(Mice, Inbred C57BL);细胞系, 肿瘤(Cell Line, Tumor);人类(Humans);淋巴细胞, 肿瘤浸润(Lymphocytes, Tumor-Infiltrating);骨髓细胞(Bone Marrow Cells)
DOI
10.1038/s41423-024-01202-5
PMID
39044027
发布时间
2024-10-03
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Cellular & molecular immunology
2024年21卷10期
1145-1157页
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