Cysteine protease cathepsin B promotes lysosome integrity to extend the lifespan of alternative day fasting worms.

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第一作者： Xue,Yin

第一单位： School of Basic Medical Sciences, Henan University, Kaifeng, China.

作者： Xue,Yin ^[1] ; Fangzhou,Dai ^[1] ; Dongyang,Ran ^[1] ; Yutong,Zhang ^[1] ; Zhi,Qu ^[2] ; Shanqing,Zheng ^[3]

作者单位： School of Basic Medical Sciences, Henan University, Kaifeng, China. ^[1] School of Nursing and Health, Henan University, Kaifeng, China. ^[2] School of Basic Medical Sciences, Henan University, Kaifeng, China.;Laboratory of Cell Signal Transduction, Henan Provincial Engineering Centre for Tumor Molecular Medicine, Medical School of Henan University, Kaifeng, China.;The Zhongzhou Laboratory for Integrative Biology, Zhengzhou, Henan, China. ^[3]

关键词 C. elegans alternative day fasting cysteine protease cathepsin B lifespan lysosome

主题词动物(Animals);秀丽新小杆线虫(Caenorhabditis elegans);组织蛋白酶B(Cathepsin B);溶酶体(Lysosomes);长寿(Longevity);禁食(Fasting);漂亮新小杆线虫蛋白质类(Caenorhabditis elegans Proteins)

DOI 10.1111/acel.14286

PMID 39046045

发布时间 2024-11-16

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