Microcystin-LR prenatal exposure induces coronary heart disease through macrophage polarization imbalance mediated by trophoblast-derived extracellular vesicles.

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第一作者： Meihong,Guo

第一单位： State Key Laboratory of Analytical Chemistry for Life Science, Division of Anatomy and Histo-embryology, Medical School, Nanjing University, Nanjing, Jiangsu 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, Jiangsu 210093, China.

作者： Meihong,Guo ^[1] ; Xinrui,Li ^[1] ; Manhou,Choi ^[1] ; Jingwen,Zhang ^[1] ; Songci,Yan ^[1] ; Danni,Ma ^[1] ; Jing,Zeng ^[1] ; Weidong,Ding ^[1] ; Yanting,Wen ^[1] ; Dongmei,Li ^[1] ; Xiaodong,Han ^[1] ; Yong,Wang ^[2] ; Jiang,Wu ^[3]

作者单位： State Key Laboratory of Analytical Chemistry for Life Science, Division of Anatomy and Histo-embryology, Medical School, Nanjing University, Nanjing, Jiangsu 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, Jiangsu 210093, China. ^[1] State Key Laboratory of Analytical Chemistry for Life Science, Division of Anatomy and Histo-embryology, Medical School, Nanjing University, Nanjing, Jiangsu 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, Jiangsu 210093, China. Electronic address: yongwang@nju.edu.cn. ^[2] State Key Laboratory of Analytical Chemistry for Life Science, Division of Anatomy and Histo-embryology, Medical School, Nanjing University, Nanjing, Jiangsu 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, Jiangsu 210093, China. Electronic address: wujiang@nju.edu.cn. ^[3]

关键词 Congenital heart disease Macrophage Microcystin-LR Trophoblastic-derived vesicles miR-377-3p