Pterocarpus soyauxii (Fabaceae) aqueous extract to prevent neuropsychiatric disorders associated with menopause by triggering ROS-dependent oxidative damage and inhibiting acetylcholinesterase, GABA-transaminase, and monoamine oxidase A: In vitro, in vivo, and in silico approaches.

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第一作者： Pascal Emmanuel,Owona

第一单位： Department of Animal Biology and Physiology, Laboratory of Animal Physiology, Faculty of Science, University of Yaoundé 1, P.O. Box 812 Yaoundé, Cameroon.

作者： Pascal Emmanuel,Owona ^[1] ; Yolande Sandrine,Mengue Ngadena ^[2] ; Danielle Claude,Bilanda ^[1] ; Madeleine Chantal,Ngoungouré ^[1] ; Lohik,Mbolang Nguegan ^[1] ; Ronald,Bidingha A Goufani ^[1] ; Rivaldo Bernes,Kahou Tadah ^[1] ; Michel,Noubom ^[3] ; Armand Fils,Ella ^[4] ; Yannick Carlos,Tcheutchoua ^[1] ; Bruno Dupon,Ambamba Akamba ^[4] ; Paule Cynthia,Bouguem Yandja ^[1] ; Paulin,Keumedjio Teko ^[4] ; Paul Desire,Dzeufiet Djomeni ^[1] ; Pierre,Kamtchouing ^[1]

作者单位： Department of Animal Biology and Physiology, Laboratory of Animal Physiology, Faculty of Science, University of Yaoundé 1, P.O. Box 812 Yaoundé, Cameroon. ^[1] Department of Animal Biology and Physiology, Laboratory of Animal Physiology, Faculty of Science, University of Yaoundé 1, P.O. Box 812 Yaoundé, Cameroon.;Neurosciences and psychogerontology axis, Laboratory of Development and Maldevelopment, Department of Psychology, Faculty of Arts, Letters, and Social Science, University of Yaoundé 1, P.O. Box. 755 Yaoundé, Cameroon. ^[2] Department of Biological Sciences, Faculty of Medicine, University of Dschang, P.O. Box. 67, Dschang, Cameroon. ^[3] Department of Biochemistry, Laboratory of Pharmacology and Toxicology, Faculty of Science, University of Yaoundé 1, P.O. Box 812 Yaoundé, Cameroon. ^[4]

关键词 Anti-inflammatory Antioxidant Menopause Neurological disorders Neuroprotective Pterocarpus soyauxii

DOI 10.1016/j.heliyon.2024.e33843

PMID 39055825

发布时间 2024-07-27

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2024年10卷13期

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