Targeting Microglia in Neuroinflammation: H3 Receptor Antagonists as a Novel Therapeutic Approach for Alzheimer's Disease, Parkinson's Disease, and Autism Spectrum Disorder.

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作者： Shilu Deepa,Thomas ^[1] ; Sabna,Abdalla ^[1] ; Nermin,Eissa ^[2] ; Amal,Akour ^[3] ; Niraj Kumar,Jha ^[4] ; Shreesh,Ojha ^[1] ; Bassem,Sadek ^[1]

作者单位： Department of Pharmacology & Therapeutics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.;Zayed Center for Health Sciences, United Arab Emirates University, Al-Ain P.O. Box 1551, United Arab Emirates. ^[1] Department of Biomedical Sciences, College of Health Sciences, Abu Dhabi University, Abu Dhabi P.O. Box 59911, United Arab Emirates. ^[2] Department of Pharmacology & Therapeutics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.;Zayed Center for Health Sciences, United Arab Emirates University, Al-Ain P.O. Box 1551, United Arab Emirates.;Department of Biopharmaceutics and Clinical Pharmacy, School of Pharmacy, The University of Jordan, Amman 11942, Jordan. ^[3] Centre for Global Health Research, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 602105, India.;Centre of Research Impact and Outcome, Chitkara University, Rajpura 140401, India.;School of Bioengineering & Biosciences, Lovely Professional University, Phagwara 144411, India.;Department of Biotechnology, School of Applied & Life Sciences (SALS), Uttaranchal University, Dehradun 248007, India. ^[4]

关键词 Alzheimer’s disease H3R antagonists Parkinson’s disease amyloid beta (Aβ)autism spectrum disorder cytokines microglia neurogenesis neuroinflammation α-synuclein

DOI 10.3390/ph17070831

PMID 39065682

发布时间 2024-07-29

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