首页> Journal of medicinal chemistry> Genomic Discovery and Structure-Activity Exploration of a Novel Family of Enzyme-Activated Covalent Cyclin-Dependent Kinase Inhibitors.

Genomic Discovery and Structure-Activity Exploration of a Novel Family of Enzyme-Activated Covalent Cyclin-Dependent Kinase Inhibitors.

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第一作者： Jack R,Davison

第一单位： LifeMine Therapeutics, 30 Acorn Park Drive, Cambridge, Massachusetts 02140, United States.

作者： Jack R,Davison ^[1] ; Michalis,Hadjithomas ^[1] ; Stuart P,Romeril ^[1] ; Yoon Jong,Choi ^[1] ; Keith W,Bentley ^[1] ; John B,Biggins ^[1] ; Nadia,Chacko ^[1] ; M Paola,Castaldi ^[1] ; Lawrence K,Chan ^[1] ; Jared N,Cumming ^[1] ; Thomas D,Downes ^[1] ; Eric L,Eisenhauer ^[1] ; Fan,Fei ^[1] ; Benjamin M,Fontaine ^[1] ; Venkatesh,Endalur Gopinarayanan ^[1] ; Srishti,Gurnani ^[1] ; Audrey,Hecht ^[1] ; Christopher J,Hosford ^[1] ; Ashraf,Ibrahim ^[1] ; Annika,Jagels ^[1] ; Camil,Joubran ^[1] ; Ji-Nu,Kim ^[1] ; John P,Lisher ^[1] ; Daniel D,Liu ^[1] ; James T,Lyles ^[1] ; Matteo N,Mannara ^[1] ; Gordon J,Murray ^[1] ; Emilia,Musial ^[1] ; Mengyao,Niu ^[1] ; Roberto,Olivares-Amaya ^[1] ; Marielle,Percuoco ^[1] ; Susanne,Saalau ^[1] ; Kristen,Sharpe ^[1] ; Anjali V,Sheahan ^[1] ; Neroshan,Thevakumaran ^[1] ; James E,Thompson ^[1] ; Dawn A,Thompson ^[1] ; Aric,Wiest ^[1] ; Stephen A,Wyka ^[1] ; Jason,Yano ^[1] ; Gregory L,Verdine ^[2]

作者单位： LifeMine Therapeutics, 30 Acorn Park Drive, Cambridge, Massachusetts 02140, United States. ^[1] LifeMine Therapeutics, 30 Acorn Park Drive, Cambridge, Massachusetts 02140, United States.;Departments of Chemistry and Chemical Biology, and Stem Cell and Regenerative Biology, Harvard University and Harvard Medical School, 12 Oxford Street, Cambridge, Massachusetts 02138, United States. ^[2]