ORC1 enhances repressive epigenetic modifications on HIV-1 LTR to promote HIV-1 latency.

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作者： Mo,Zhou ^[1] ; Tao,Yang ^[2] ; Ming,Yuan ^[2] ; Xinyu,Li ^[3] ; Jieyi,Deng ^[2] ; Shiyu,Wu ^[2] ; Zhihan,Zhong ^[2] ; Yingtong,Lin ^[2] ; Wanying,Zhang ^[2] ; Baijin,Xia ^[4] ; Yating,Wu ^[4] ; Lilin,Wang ^[5] ; Tao,Chen ^[6] ; Ruxin,Liu ^[3] ; Ting,Pan ^[3] ; Xiancai,Ma ^[6] ; Linghua,Li ^[7] ; Bingfeng,Liu ^[2] ; Hui,Zhang ^[2]

作者单位： Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China.;Center for Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China. ^[1] Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China. ^[2] Shenzhen Key Laboratory of Systems Medicine for Inflammatory Diseases, School of Medicine, Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong, China. ^[3] Medical Research Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Science), Guangzhou, China. ^[4] Shenzhen Blood Center, Shenzhen, Guangdong, China. ^[5] Guangzhou National Laboratory, Guangzhou International Bio-Island, Guangzhou, China. ^[6] Center for Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China. ^[7]

关键词 HIV-1 latency LLPS LTR-associated factors ORC1 repressive epigenetic modifications