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Zonation and ligand and dose dependence of sphingosine 1-phosphate receptor-1 signalling in blood and lymphatic vasculature.

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第一作者： Ilaria,Del Gaudio

第一单位： Université Paris Cité, Paris Cardiovascular Research Centre, INSERM U970, 56 Rue Leblanc, F-75015 Paris, France.

作者： Ilaria,Del Gaudio ^[1] ; Anja,Nitzsche ^[1] ; Kevin,Boyé ^[1] ; Philippe,Bonnin ^[2] ; Mathilde,Poulet ^[1] ; Toan Q,Nguyen ^[3] ; Ludovic,Couty ^[1] ; Hoa T T,Ha ^[3] ; Dat T,Nguyen ^[3] ; Amaury,Cazenave-Gassiot ^[3] ; Khaoula,Ben Alaya ^[1] ; Patrice,Thérond ^[4] ; Jerold,Chun ^[5] ; Markus R,Wenk ^[3] ; Richard L,Proia ^[6] ; Daniel,Henrion ^[7] ; Long N,Nguyen ^[3] ; Anne,Eichmann ^[8] ; Eric,Camerer ^[1]

作者单位： Université Paris Cité, Paris Cardiovascular Research Centre, INSERM U970, 56 Rue Leblanc, F-75015 Paris, France. ^[1] Physiologie Clinique, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Lariboisière, Paris, France.;Université Paris Cité, INSERM U1144, UFR de Pharmacie, Paris, France. ^[2] Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117596, Singapore. ^[3] Service de Biochimie, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital de Bicêtre, Le Kremlin Bicêtre, France.;UFR de Pharmacie, EA 4529, Châtenay-Malabry, France. ^[4] Neuroscience Drug Discovery, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA. ^[5] National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Institutes of Health, Bethesda, MD, USA. ^[6] MitoVasc Department, Angers University, Team 2 (CarMe), Angers University Hospital (CHU of Angers), CNRS, INSERM U1083, Angers, France. ^[7] Université Paris Cité, Paris Cardiovascular Research Centre, INSERM U970, 56 Rue Leblanc, F-75015 Paris, France.;Department of Internal Medicine and Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, USA. ^[8]

关键词 Endothelial function Signalling Sphingosine 1-phosphate Vascular biology Vascular integrity