Evidence for NR2F2/COUP-TFII involvement in human testis development.

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作者： Somboon,Wankanit ^[1] ; Housna,Zidoune ^[2] ; Joëlle,Bignon-Topalovic ^[3] ; Laurène,Schlick ^[3] ; Denis,Houzelstein ^[3] ; Leila,Fusée ^[3] ; Asma,Boukri ^[4] ; Nassim,Nouri ^[4] ; Ken,McElreavey ^[3] ; Anu,Bashamboo ^[3] ; Maëva,Elzaiat ^[5]

作者单位： Human Developmental Genetics Unit, CNRS UMR 3738, Institut Pasteur, 75015, Paris, France.;Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand. ^[1] Human Developmental Genetics Unit, CNRS UMR 3738, Institut Pasteur, 75015, Paris, France.;Department of Animal Biology, Laboratory of Molecular and Cellular Biology, University Frères Mentouri Constantine 1, 25017, Constantine, Algeria. ^[2] Human Developmental Genetics Unit, CNRS UMR 3738, Institut Pasteur, 75015, Paris, France. ^[3] Department of Endocrinology and Diabetology, CHU Ibn Badis Constantine, Constantine, Algeria.;Metabolic Disease Research Laboratory, Salah Boubnider Constantine 3 University, El Khroub, Algeria. ^[4] Human Developmental Genetics Unit, CNRS UMR 3738, Institut Pasteur, 75015, Paris, France. maeva.el-zaiat-munsch@pasteur.fr. ^[5]

关键词 46,XY disorders/differences of sex development/differentiation (DSD)COUP-TFII NR2F2 Sex determination Under-virilization

主题词人类(Humans);COUP转录因子Ⅱ(COUP Transcription Factor II);睾丸(Testis);男(雄)性(Male);类固醇生成因子1(Steroidogenic Factor 1);突变(Mutation);性腺功能减退症(Hypogonadism)

DOI 10.1038/s41598-024-68860-3

PMID 39090159

发布时间 2024-08-16

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