An Alternatively Spliced Gain-of-Function NT5C2 Isoform Contributes to Chemoresistance in Acute Lymphoblastic Leukemia.

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第一作者： Manuel,Torres-Diz

第一单位： Division of Cancer Pathobiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

作者： Manuel,Torres-Diz ^[1] ; Clara,Reglero ^[2] ; Catherine D,Falkenstein ^[3] ; Annette,Castro ^[1] ; Katharina E,Hayer ^[4] ; Caleb M,Radens ^[5] ; Mathieu,Quesnel-Vallières ^[6] ; Zhiwei,Ang ^[1] ; Priyanka,Sehgal ^[1] ; Marilyn M,Li ^[7] ; Yoseph,Barash ^[5] ; Sarah K,Tasian ^[8] ; Adolfo,Ferrando ^[9] ; Andrei,Thomas-Tikhonenko ^[10]

作者单位： Division of Cancer Pathobiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. ^[1] Institute for Cancer Genetics, Columbia University, New York, New York. ^[2] Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. ^[3] Division of Cancer Pathobiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.;Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. ^[4] Cell and Molecular Biology Graduate Group, University of Pennsylvania, Philadelphia, Pennsylvania.;Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. ^[5] Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. ^[6] Division of Genomic Diagnostic, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.;Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. ^[7] Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.;Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. ^[8] Institute for Cancer Genetics, Columbia University, New York, New York.;Department of Pediatrics, Columbia University, New York, New York. ^[9] Division of Cancer Pathobiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.;Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.;Cell and Molecular Biology Graduate Group, University of Pennsylvania, Philadelphia, Pennsylvania.;Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.;Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. ^[10]