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Genome-wide CRISPR screening identifies tyrosylprotein sulfotransferase-2 as a target for augmenting anti-PD1 efficacy.

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作者: Yumi,Oh [1] ; Sujeong,Kim [2] ; Yunjae,Kim [2] ; Hyun,Kim [2] ; Dongjun,Jang [3] ; Seungjae,Shin [3] ; Soo-Jin,Lee [3] ; Jiwon,Kim [3] ; Sang Eun,Lee [3] ; Jaeik,Oh [4] ; Yoojin,Yang [3] ; Dohee,Kim [3] ; Hae Rim,Jung [1] ; Sangjin,Kim [2] ; Jihui,Kim [2] ; Kyungchan,Min [2] ; Beomki,Cho [2] ; Hoseok,Seo [5] ; Dohyun,Han [6] ; Hansoo,Park [7] ; Sung-Yup,Cho [8]
作者单位: Medical Research Center, Genomic Medicine Institute, Seoul National University College of Medicine, Seoul, 03080, Korea. [1] Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, Korea. [2] Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, Korea. [3] Department of Translational Medicine, Seoul National University College of Medicine, Seoul, 03080, Korea. [4] Department of Transdisciplinary Medicine, Seoul National University Hospital, Seoul, 03080, Korea.;Interdisciplinary Program in Neuroscience, College of Natural Sciences, Seoul National University, Seoul, 08826, Korea. [5] Department of Transdisciplinary Medicine, Seoul National University Hospital, Seoul, 03080, Korea.;Department of Medicine, Seoul National University College of Medicine, Seoul, 03080, Korea. [6] Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, 61005, Korea. hspark27@gist.ac.kr.;Genome&Company, Suwon, 16229, Korea. hspark27@gist.ac.kr. [7] Medical Research Center, Genomic Medicine Institute, Seoul National University College of Medicine, Seoul, 03080, Korea. csybio@snu.ac.kr.;Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, 03080, Korea. csybio@snu.ac.kr.;Department of Translational Medicine, Seoul National University College of Medicine, Seoul, 03080, Korea. csybio@snu.ac.kr.;Cancer Research Institute, Seoul National University, Seoul, 03080, Korea. csybio@snu.ac.kr. [8]
DOI 10.1186/s12943-024-02068-x
PMID 39095793
发布时间 2024-08-07
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