Therapeutic targeting of siRNA/anti-cancer drug delivery system for non-melanoma skin cancer. Part I: Development and gene silencing of JAK1siRNA/5-FU loaded liposome nanocomplexes.

导出 LinkOut

翻译打印收藏纠错

第一作者： Minela,Aslan

第一单位： Bioengineering Division, Institute for Graduate Studies in Science and Engineering, Hacettepe University, Ankara, Turkey.

作者： Minela,Aslan ^[1] ; Sukru,Ozturk ^[2] ; Reza,Shahbazi ^[3] ; Özlem,Bozdemir ^[4] ; Naciye,Dilara Zeybek ^[5] ; İbrahim,Vargel ^[6] ; İpek,Eroğlu ^[7] ; Kezban,Ulubayram ^[8]

作者单位： Bioengineering Division, Institute for Graduate Studies in Science and Engineering, Hacettepe University, Ankara, Turkey. ^[1] Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey. ^[2] School of Medicine, Indiana University, Indianapolis, IN. ^[3] Department of Stem Cell Sciences, Graduate School of Health Sciences, Hacettepe University, Ankara, Turkey. ^[4] Department of Histology and Embryology, Faculty of Medicine, Hacettepe University, Ankara, Turkey. ^[5] Department of Plastic, Reconstructive and Aesthetic Surgery, Faculty of Medicine, Hacettepe University, Ankara, Turkey. ^[6] Bioengineering Division, Institute for Graduate Studies in Science and Engineering, Hacettepe University, Ankara, Turkey; Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey. Electronic address: ipekeroglu@hacettepe.edu.tr. ^[7] Bioengineering Division, Institute for Graduate Studies in Science and Engineering, Hacettepe University, Ankara, Turkey; Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey. Electronic address: ukezban@hacettepe.edu.tr. ^[8]

关键词 5-FU JAK1 gene silencing Janus kinase 1 Liposomes NMSC cancer therapy Non-melanoma skin cancer siRNA delivery