Circadian clock component PER2 negatively regulates CD4<sup>+</sup> T cell IFN-γ production in ulcerative colitis.
第一作者:
Yulan,Ye
第一单位:
Center for IBD Research and Department of Gastroenterology, The Shanghai Tenth People's Hospital of Tongji University, Shanghai 200072, China; Department of Gastroenterology, Suzhou Municipal Hospital Affiliated to Nanjing Medical University, Suzhou 215008, China.
作者:
主题词
人类(Humans);结肠炎, 溃疡性(Colitis, Ulcerative);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);男(雄)性(Male);女(雌)性(Female);干扰素γ(Interferon-gamma);成年人(Adult);周期昼夜节律蛋白质类(Period Circadian Proteins);中年人(Middle Aged);昼夜节律钟(Circadian Clocks);Crohn病(Crohn Disease);基因表达调控(Gene Expression Regulation);肠黏膜(Intestinal Mucosa);细胞, 培养的(Cells, Cultured);疾病严重程度指数(Severity of Illness Index)
DOI
10.1016/j.mucimm.2024.07.010
PMID
39097147
发布时间
2024-12-12
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Mucosal immunology
1161-1173页
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