Morin overcomes doxorubicin resistance in human breast cancer by inducing DNA damage and modulating the LKB1/AMPK/mTORC1 signaling pathway.
第一作者:
Sushma,Maharjan
第一单位:
Department of Pharmacology and Intractable Disease Research Center, School of Medicine, Dongguk University, Gyeongju, Republic of Korea.
作者:
主题词
人类(Humans);类黄酮物质(Flavonoids);女(雌)性(Female);乳腺肿瘤(Breast Neoplasms);多柔比星(Doxorubicin);DNA损伤(DNA Damage);信号传导(Signal Transduction);抗药性, 肿瘤(Drug Resistance, Neoplasm);动物(Animals);小鼠(Mice);AMP活化蛋白激酶类(AMP-Activated Protein Kinases);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays);细胞系, 肿瘤(Cell Line, Tumor);小鼠, 裸(Mice, Nude);细胞凋亡(Apoptosis);小鼠, 近交BALB C(Mice, Inbred BALB C);黄酮类(Flavones)
DOI
10.1002/biof.2112
PMID
39114963
发布时间
2024-12-28
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BioFactors (Oxford, England)
e2112页
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