Regulatory B Cells Expressing Granzyme B from Tolerant Renal Transplant Patients: Highly Differentiated B Cells with a Unique Pathway with a Specific Regulatory Profile and Strong Interactions with Immune System Cells.

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作者： Nicolas,Sailliet ^[1] ; Amandine,Dupuy ^[1] ; François,Brinas ^[1] ; Karine,Renaudin ^[2] ; Luc,Colas ^[1] ; Clarisse,Kerleau ^[1] ; Thi-Van-Ha,Nguyen ^[1] ; Cynthia,Fourgeux ^[1] ; Jérémie,Poschmann ^[1] ; Clément,Gosset ^[3] ; Magali,Giral ^[4] ; Nicolas,Degauque ^[1] ; Hoa Le,Mai ^[1] ; Richard,Danger ^[1] ; Sophie,Brouard ^[4] ; DIVAT Consortium

作者单位： CHU Nantes, Nantes Université, INSERM, Center for Research in Transplantation and Translational Immunology (CR2TI), UMR 1064, ITUN, 44000 Nantes, France. ^[1] CHU Nantes, Nantes Université, INSERM, Center for Research in Transplantation and Translational Immunology (CR2TI), UMR 1064, ITUN, 44000 Nantes, France.;CHU Nantes, Service d'Anatomie et Cytologie Pathologiques, 44000 Nantes, France. ^[2] Service de Néphrologie et Transplantation rénale-CHU Pasteur2, 06000 Nice, France. ^[3] CHU Nantes, Nantes Université, INSERM, Center for Research in Transplantation and Translational Immunology (CR2TI), UMR 1064, ITUN, 44000 Nantes, France.;Centre d'Investigation Clinique en Biothérapie, Centre de Ressources Biologiques (CRB), CHU Nantes, 44000 Nantes, France.;LabEx IGO "Immunotherapy, Graft, Oncology", Nantes Université, 44000 Nantes, France. ^[4]

关键词 B cells kidney lymphocyte regulation tolerance transplantation

主题词人类(Humans);颗粒酶类(Granzymes);肾移植(Kidney Transplantation);细胞分化(Cell Differentiation);女(雌)性(Female);男(雄)性(Male);免疫系统(Immune System);中年人(Middle Aged);移植物排斥(Graft Rejection);杀伤细胞, 天然(Killer Cells, Natural);白细胞, 单核(Leukocytes, Mononuclear)

DOI 10.3390/cells13151287

PMID 39120317

发布时间 2025-01-23

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Cells

2024年13卷15期

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Regulatory B Cells Expressing Granzyme B from Tolerant Renal Transplant Patients: Highly Differentiated B Cells with a Unique Pathway with a Specific Regulatory Profile and Strong Interactions with Immune System Cells.

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Regulatory B Cells Expressing Granzyme B from Tolerant Renal Transplant Patients: Highly Differentiated B Cells with a Unique Pathway with a Specific Regulatory Profile and Strong Interactions with Immune System Cells.

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