CircUGP2 Suppresses Intrahepatic Cholangiocarcinoma Progression via p53 Signaling Through Interacting With PURB to Regulate ADGRB1 Transcription and Sponging miR-3191-5p.

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第一作者： Rui Xiang,Chen

第一单位： Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Key Laboratory of Liver Transplantation, Chinese Academy of Medical Sciences, NHC Key Laboratory of Living Donor Liver Transplantation (Nanjing Medical University), Nanjing, Jiangsu, 210029, China.

作者： Rui Xiang,Chen ^[1] ; Shuo Chen,Liu ^[1] ; Xue Chun,Kan ^[2] ; Yi Rui,Wang ^[1] ; Ji Fei,Wang ^[1] ; Tian Lin,Wang ^[1] ; Chang,Li ^[1] ; Wang Jie,Jiang ^[1] ; Yan An Lan,Chen ^[1] ; Tao,Zhou ^[1] ; Shi Long,Fan ^[1] ; Jiang,Chang ^[1] ; Xiao,Xu ^[1] ; Kuang Heng,Shi ^[1] ; Yao Dong,Zhang ^[1] ; Ming Yu,Wu ^[3] ; Yue,Yu ^[1] ; Chang Xian,Li ^[1] ; Xiang Cheng,Li ^[4]

作者单位： Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Key Laboratory of Liver Transplantation, Chinese Academy of Medical Sciences, NHC Key Laboratory of Living Donor Liver Transplantation (Nanjing Medical University), Nanjing, Jiangsu, 210029, China. ^[1] School of Medicine, Southeast University, Nanjing, Jiangsu, 210009, China. ^[2] The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, 214023, China. ^[3] Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Key Laboratory of Liver Transplantation, Chinese Academy of Medical Sciences, NHC Key Laboratory of Living Donor Liver Transplantation (Nanjing Medical University), Nanjing, Jiangsu, 210029, China.;The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, 214023, China. ^[4]

关键词 ADGRB1 PURB circUGP2 intrahepatic cholangiocarcinoma lipid nanoparticles p53 signaling

主题词胆管上皮癌(Cholangiocarcinoma);人类(Humans);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53);小鼠(Mice);疾病恶化(Disease Progression);微RNAs(MicroRNAs);胆管肿瘤(Bile Duct Neoplasms);信号传导(Signal Transduction);动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);疾病模型, 动物(Disease Models, Animal);男(雄)性(Male)

DOI 10.1002/advs.202402329

PMID 39120980

发布时间 2024-10-18

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

2024年11卷38期

e2402329页

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CircUGP2 Suppresses Intrahepatic Cholangiocarcinoma Progression via p53 Signaling Through Interacting With PURB to Regulate ADGRB1 Transcription and Sponging miR-3191-5p.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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CircUGP2 Suppresses Intrahepatic Cholangiocarcinoma Progression via p53 Signaling Through Interacting With PURB to Regulate ADGRB1 Transcription and Sponging miR-3191-5p.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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