Polθ: emerging synthetic lethal partner in homologous recombination-deficient tumors.

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作者： Tancredi Didier,Bazan Russo ^[1] ; Clarissa,Mujacic ^[1] ; Emilia,Di Giovanni ^[1] ; Maria Concetta,Vitale ^[1] ; Carla,Ferrante Bannera ^[1] ; Ugo,Randazzo ^[1] ; Silvia,Contino ^[1] ; Marco,Bono ^[1] ; Valerio,Gristina ^[1] ; Antonio,Galvano ^[1] ; Alessandro,Perez ^[1] ; Giuseppe,Badalamenti ^[2] ; Antonio,Russo ^[3] ; Viviana,Bazan ^[4] ; Lorena,Incorvaia ^[1]

作者单位： Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), Section of Medical Oncology, University of Palermo, 90127, Palermo, Italy. ^[1] Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), Section of Medical Oncology, University of Palermo, 90127, Palermo, Italy. giuseppe.badalamenti@unipa.it. ^[2] Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), Section of Medical Oncology, University of Palermo, 90127, Palermo, Italy. antonio.russo@usa.net. ^[3] Department of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), Section of Medical Oncology, University of Palermo, 90127, Palermo, Italy. ^[4]

主题词人类(Humans);指导DNA的DNA聚合酶(DNA-Directed DNA Polymerase);肿瘤(Neoplasms);动物(Animals);BRCA2蛋白质(BRCA2 Protein)

DOI 10.1038/s41417-024-00815-2

PMID 39122831

发布时间 2024-11-22

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