Dynamics of scFv-targeted VAP2 correlating with IL-16, MIF and IL-1Ra in ANCA-associated vasculitis.

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第一作者： Junya,Suzuki

第一单位： Department of Allergy and Clinical Immunology, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba-city, Chiba 260-8677, Japan.

作者： Junya,Suzuki ^[1] ; Shunsuke,Furuta ^[1] ; Yosuke,Kameoka ^[2] ; Osamu,Suzuki ^[3] ; Fuyu,Ito ^[4] ; Kazuko,Uno ^[5] ; Fukuko,Kishi ^[2] ; Yoshio,Yamakawa ^[2] ; Kazuyuki,Matsushita ^[6] ; Takashi,Miki ^[7] ; Hiroshi,Nakajima ^[1] ; Kazuo,Suzuki ^[8]

作者单位： Department of Allergy and Clinical Immunology, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba-city, Chiba 260-8677, Japan. ^[1] A-CLIP Institute, Minami-cho 2-17-13, Chyuo-ku, Chiba-city, Chiba 260-0842, Japan. ^[2] National Institutes of Biomedical Innovation, Health and Nutrition, 7-6-8 Saito-Asagi, Ibaraki-city, Osaka 567-0085, Japan. ^[3] Asia International Institute of Infectious Disease Control, Itabashi-ku, Tokyo, Teikyo University, Japan. ^[4] Louis Pasteur Center for Medical Research, 103-5 Tanaka Monzen-cho, Sakyo-ku, Kyoto 606-8225, Japan. ^[5] Department of Laboratory Medicine, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba-city, Chiba 260-8677, Japan. ^[6] Research Institute of Disaster Medicine, Chiba University, Division of Co-creative Research in Disaster Therapeutics, 1-8-1 Inohana, Chuo-ku, Chiba-city, Chiba 260-8670, Japan. ^[7] A-CLIP Institute, Minami-cho 2-17-13, Chyuo-ku, Chiba-city, Chiba 260-0842, Japan; Louis Pasteur Center for Medical Research, 103-5 Tanaka Monzen-cho, Sakyo-ku, Kyoto 606-8225, Japan; Research Institute of Disaster Medicine, Chiba University, Division of Co-creative Research in Disaster Therapeutics, 1-8-1 Inohana, Chuo-ku, Chiba-city, Chiba 260-8670, Japan. Electronic address: ksuzuki@a-clip.jp. ^[8]

关键词 Cytokines Microscopic polyangiitis Myeloperoxidase Recombinant scFv of human immunoglobulin G Target molecule vasculitis-associated apolipoprotein 2