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首页> Cancer gene therapy> The splicing factor SF3B1 confers ferroptosis resistance and promotes lung adenocarcinoma progression via upregulation of SLC7A11.

The splicing factor SF3B1 confers ferroptosis resistance and promotes lung adenocarcinoma progression via upregulation of SLC7A11.

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作者： Yanlin,Guo ^[1] ; Xiaohui,Wang ^[1] ; Yu,Du ^[2] ; Yixuan,Zhao ^[1] ; Lvye,Gao ^[1] ; Yanlong,Hao ^[1] ; Dou,Lv ^[3] ; Xuefei,Feng ^[1] ; Yuanfang,Zhai ^[1] ; Binbin,Zou ^[1] ; Jinli,Han ^[3] ; Enwei,Xu ^[4] ; Yue,Yang ^[5] ; Bin,Yang ^[5] ; Yanfeng,Xi ^[6] ; Ling,Zhang ^[7]

作者单位： Basic Medical Sciences Center of Shanxi Medical University, Taiyuan, 030001, Shanxi, China. ^[1] Basic Medical Sciences Center of Shanxi Medical University, Taiyuan, 030001, Shanxi, China.;Shanxi Inspection and Testing Center, Taiyuan, 030031, Shanxi, China. ^[2] Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, Shanxi, China. ^[3] Department of Pathology, Shanxi Cancer Hospital, Taiyuan, 030001, Shanxi, China. ^[4] Department of Thoracic Surgery, Shanxi Cancer Hospital, Taiyuan, 030001, Shanxi, China. ^[5] Department of Pathology, Shanxi Cancer Hospital, Taiyuan, 030001, Shanxi, China. xiyanfeng1998@163.com. ^[6] Basic Medical Sciences Center of Shanxi Medical University, Taiyuan, 030001, Shanxi, China. zhanglingty@sxmu.edu.cn. ^[7]

主题词人类(Humans);小鼠(Mice);肺肿瘤(Lung Neoplasms);氨基酸转运系统y+(Amino Acid Transport System y+);动物(Animals);增量调节(Up-Regulation);疾病恶化(Disease Progression);男(雄)性(Male);女(雌)性(Female);磷蛋白类(Phosphoproteins);细胞系, 肿瘤(Cell Line, Tumor);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);细胞增殖(Cell Proliferation);小鼠, 裸(Mice, Nude)

DOI 10.1038/s41417-024-00817-0

PMID 39127833

发布时间 2024-10-22

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Cancer gene therapy

Cancer gene therapy

2024年31卷10期

1498-1510页

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