首页> Antimicrobial agents and chemotherapy> ARGONAUT-III and -V: susceptibility of carbapenem-resistant Klebsiella pneumoniae and multidrug-resistant Pseudomonas aeruginosa to the bicyclic boronate β-lactamase inhibitor taniborbactam combined with cefepime.

ARGONAUT-III and -V: susceptibility of carbapenem-resistant Klebsiella pneumoniae and multidrug-resistant Pseudomonas aeruginosa to the bicyclic boronate β-lactamase inhibitor taniborbactam combined with cefepime.

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第一作者： Michael R,Jacobs

第一单位： Case Western Reserve University, Cleveland, Ohio, USA.;University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.

作者： Michael R,Jacobs ^[1] ; Ayman M,Abdelhamed ^[2] ; Caryn E,Good ^[2] ; Andrew R,Mack ^[3] ; Christopher R,Bethel ^[4] ; Steven,Marshall ^[4] ; Andrea M,Hujer ^[5] ; Kristine M,Hujer ^[5] ; Robin,Patel ^[6] ; David,van Duin ^[7] ; Vance G,Fowler ^[8] ; Daniel D,Rhoads ^[9] ; David A,Six ^[10] ; Greg,Moeck ^[10] ; Tsuyoshi,Uehara ^[10] ; Krisztina M,Papp-Wallace ^[11] ; Robert A,Bonomo ^[12]

作者单位： Case Western Reserve University, Cleveland, Ohio, USA.;University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA. ^[1] University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA. ^[2] Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.;Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Research Service, Cleveland, Ohio, USA. ^[3] Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Research Service, Cleveland, Ohio, USA. ^[4] Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Research Service, Cleveland, Ohio, USA.;Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA. ^[5] Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA. ^[6] Division of Infectious Diseases, University of North Carolina, Chapel Hill, North Carolina, USA. ^[7] Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA. ^[8] Case Western Reserve University, Cleveland, Ohio, USA.;Department of Pathology, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, USA. ^[9] Venatorx Pharmaceuticals Inc., Malvern, Pennsylvania, USA. ^[10] Case Western Reserve University, Cleveland, Ohio, USA.;Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Research Service, Cleveland, Ohio, USA. ^[11] Department of Molecular Biology and Microbiology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.;Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Research Service, Cleveland, Ohio, USA.;Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.;Departments of Biochemistry, Pharmacology, Proteomics and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.;CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (Case VA CARES), Cleveland, Ohio, USA. ^[12]

关键词 Klebsiella pneumoniae Pseudomonas aeruginosa beta-lactamase inhibitor bicyclic boronate cefepime taniborbactam taniborbactam