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Enhancing mutation detection in multiple myeloma with an error-corrected ultra-sensitive NGS assay without plasma cell enrichment.

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第一作者： Jin Ju,Kim

第一单位： Department of Laboratory Medicine, Yonsei University College of Medicine, Yongin Severance Hospital, Yongin, Korea.

作者： Jin Ju,Kim ^[1] ; Soo-Jeong,Kim ^[2] ; Seoyoung,Lim ^[3] ; Seung-Tae,Lee ^[4] ; Jong Rak,Choi ^[4] ; Saeam,Shin ^[5] ; Doh Yu,Hwang ^[6]

作者单位： Department of Laboratory Medicine, Yonsei University College of Medicine, Yongin Severance Hospital, Yongin, Korea. ^[1] Department of Internal Medicine, Division of Hemato-Oncology, Yonsei University College of Medicine, Yongin Severance Hospital, Yongin, Korea. ^[2] Graduate School of Medical Science, Brain Korea PLUS Project, Yonsei University College of Medicine, Seoul, Republic of Korea. ^[3] Department of Laboratory Medicine, Yonsei University College of Medicine, Severance Hospital, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea.;Dxome, Seoul, Republic of Korea. ^[4] Department of Laboratory Medicine, Yonsei University College of Medicine, Severance Hospital, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea. saeam0304@yuhs.ac. ^[5] Department of Internal Medicine, Division of Hematology, Yonsei University College of Medicine, Yongin Severance Hospital, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea. hemayu78@yuhs.ac. ^[6]

关键词 Circulating tumor DNA Error-corrected next-generation sequencing Multiple myeloma Plasma cell enrichment

DOI 10.1186/s12935-024-03470-7

PMID 39135074

发布时间 2024-08-15

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