Discovery and engineering of a novel peptide, Temporin-WY2, with enhanced in vitro and in vivo efficacy against multi-drug resistant bacteria.

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第一作者： Fengting,Liao

第一单位： School of Food and Pharmaceutical Engineering, Zhaoqing University, Zhaoqing, 526061, China.;Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region, ShaoGuan University, Shaoguan, China.;Natural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK.

作者： Fengting,Liao ^[1] ; Zhuming,Ye ^[2] ; Jinsheng,Cheng ^[3] ; Jianhua,Zhu ^[3] ; Xiaoling,Chen ^[4] ; Xiaowei,Zhou ^[5] ; Tao,Wang ^[6] ; Yangyang,Jiang ^[6] ; Chengbang,Ma ^[6] ; Mei,Zhou ^[6] ; Tianbao,Chen ^[6] ; Chris,Shaw ^[6] ; Lei,Wang ^[6]

作者单位： School of Food and Pharmaceutical Engineering, Zhaoqing University, Zhaoqing, 526061, China.;Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region, ShaoGuan University, Shaoguan, China.;Natural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK. ^[1] Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region, ShaoGuan University, Shaoguan, China.;Natural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK. ^[2] Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region, ShaoGuan University, Shaoguan, China. ^[3] Natural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK. x.chen@qub.ac.uk. ^[4] Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region, ShaoGuan University, Shaoguan, China. xzhou06@qub.ac.uk.;Natural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK. xzhou06@qub.ac.uk. ^[5] Natural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast, BT9 7BL, Northern Ireland, UK. ^[6]