In situ implantable DNA hydrogel for diagnosis and therapy of postoperative rehemorrhage following intracerebral hemorrhage surgery.

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作者： Wenyan,Yu ^[1] ; Enpeng,Gong ^[2] ; Changlin,Wang ^[3] ; Chengyuan,Che ^[4] ; Yuzhen,Zhao ^[4] ; Xinyun,Wu ^[4] ; Yi,Yang ^[4] ; Haiyu,Shi ^[4] ; Mengjuan,Chen ^[4] ; Mingge,Li ^[4] ; Li,Xie ^[4] ; Yue,Guo ^[4] ; Mingming,Guo ^[4] ; Liya,Mu ^[4] ; Zhenya,Wang ^[4] ; Zhenzhong,Zhang ^[2] ; Kaixiang,Zhang ^[3] ; Junjie,Liu ^[1] ; Jinjin,Shi ^[1]

作者单位： School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.;Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases, Zhengzhou 450001, China.;Collaborative Innovation Center of New Drug Research and Safety Evaluation, Zhengzhou 450001, China. ^[1] School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.;Collaborative Innovation Center of New Drug Research and Safety Evaluation, Zhengzhou 450001, China. ^[2] School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.;Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases, Zhengzhou 450001, China. ^[3] School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China. ^[4]

主题词脑出血(Cerebral Hemorrhage);水凝胶类(Hydrogels);血红蛋白类(Hemoglobins);动物(Animals);去铁胺(Deferoxamine);DNA(DNA);人类(Humans);男(雄)性(Male);大鼠(Rats);疾病模型, 动物(Disease Models, Animal);铁(Iron);手术后出血(Postoperative Hemorrhage);适体, 核苷(Aptamers, Nucleotide)

DOI 10.1126/sciadv.ado3919

PMID 39141742

发布时间 2024-08-14

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Science advances

2024年10卷33期

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In situ implantable DNA hydrogel for diagnosis and therapy of postoperative rehemorrhage following intracerebral hemorrhage surgery.

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In situ implantable DNA hydrogel for diagnosis and therapy of postoperative rehemorrhage following intracerebral hemorrhage surgery.

Science advances

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Science advances

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