Targeting TNFRSF25 by agonistic antibodies and multimeric TL1A proteins co-stimulated CD8<sup>+</sup> T cells and inhibited tumor growth.

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作者： Xueyuan,Lyu ^[1] ; Linlin,Zhao ^[1] ; Sijia,Chen ^[2] ; Yulu,Li ^[2] ; Yajing,Yang ^[2] ; Huisi,Liu ^[2] ; Fang,Yang ^[2] ; Wenhui,Li ^[3] ; Jianhua,Sui ^[4]

作者单位： Peking University-Tsinghua University-National Institute of Biological Sciences Joint Graduate Program, School of Life Sciences, Tsinghua University, Beijing, China.;National Institute of Biological Sciences, Beijing, China. ^[1] National Institute of Biological Sciences, Beijing, China. ^[2] National Institute of Biological Sciences, Beijing, China.;Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing, China. ^[3] National Institute of Biological Sciences, Beijing, China suijianhua@nibs.ac.cn.;Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing, China. ^[4]

关键词 Antibody Immunotherapy co-stimulatory molecules

主题词动物(Animals);小鼠(Mice);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);肿瘤坏死因子配体超家族成员15(Tumor Necrosis Factor Ligand Superfamily Member 15);人类(Humans);受体, 肿瘤坏死因子, 成员25(Receptors, Tumor Necrosis Factor, Member 25);细胞系, 肿瘤(Cell Line, Tumor);肿瘤微环境(Tumor Microenvironment);女(雌)性(Female)

DOI 10.1136/jitc-2024-008810

PMID 39142717

发布时间 2024-08-14

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Journal for immunotherapy of cancer

2024年12卷8期

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Targeting TNFRSF25 by agonistic antibodies and multimeric TL1A proteins co-stimulated CD8<sup>+</sup> T cells and inhibited tumor growth.

Journal for immunotherapy of cancer

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Journal for immunotherapy of cancer

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Targeting TNFRSF25 by agonistic antibodies and multimeric TL1A proteins co-stimulated CD8<sup>+</sup> T cells and inhibited tumor growth.

Journal for immunotherapy of cancer

相似文献

Journal for immunotherapy of cancer

相关期刊

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