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首页> International journal of cancer> Identification of epigenetic modifiers essential for growth and survival of AML1/ETO-positive leukemia.

Identification of epigenetic modifiers essential for growth and survival of AML1/ETO-positive leukemia.

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作者： Jesús,Duque-Afonso ^[1] ; Pia,Veratti ^[2] ; Usama-Ur,Rehman ^[1] ; Heike,Herzog ^[1] ; Jan,Mitschke ^[2] ; Gabriele,Greve ^[3] ; Julian,Eble ^[1] ; Bettina,Berberich ^[1] ; Johanna,Thomas ^[1] ; Milena,Pantic ^[1] ; Miguel,Waterhouse ^[1] ; Gaia,Gentile ^[1] ; Olaf,Heidenreich ^[4] ; Cornelius,Miething ^[2] ; Michael,Lübbert ^[2]

作者单位： Department of Hematology/Oncology/Stem Cell Transplantation, Faculty of Medicine, University of Freiburg Medical Center, Freiburg, Germany. ^[1] Department of Hematology/Oncology/Stem Cell Transplantation, Faculty of Medicine, University of Freiburg Medical Center, Freiburg, Germany.;German Cancer Consortium (DKTK), Partnering Site Freiburg, Freiburg, Germany. ^[2] Department of Hematology/Oncology/Stem Cell Transplantation, Faculty of Medicine, University of Freiburg Medical Center, Freiburg, Germany.;Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany. ^[3] Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands. ^[4]

关键词 ATR DNA methyltransferase acute myeloid leukemia epigenetic therapy shRNA screen

主题词人类(Humans);核心结合因子α2亚基(Core Binding Factor Alpha 2 Subunit);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);后成说, 遗传(Epigenesis, Genetic);癌基因蛋白质类, 融合(Oncogene Proteins, Fusion);细胞增殖(Cell Proliferation);细胞系, 肿瘤(Cell Line, Tumor);基因表达调控, 白血病(Gene Expression Regulation, Leukemic);RNA, 小分子干扰(RNA, Small Interfering);DNA甲基化(DNA Methylation);细胞存活(Cell Survival);细胞分化(Cell Differentiation)

DOI 10.1002/ijc.35134

PMID 39146497

发布时间 2024-10-03

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International journal of cancer

International journal of cancer

2024年155卷11期

2068-2079页

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