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Characterization of therapeutic antibody efficacy against multiple SARS-CoV-2 variants in the hamster model.

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第一作者： Yu,Cong

第一单位： Integrated Research Facility at Fort Detrick, Division of Clinical Research (DCR), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Ft. Detrick, Frederick, MD, 21702, USA.

作者： Yu,Cong ^[1] ; Saurabh,Dixit ^[1] ; Donna L,Perry ^[1] ; Louis M,Huzella ^[1] ; Erin,Kollins ^[1] ; Russell,Byrum ^[1] ; Scott M,Anthony ^[1] ; David,Drawbaugh ^[1] ; Sanae,Lembirik ^[1] ; Elena,Postnikova ^[1] ; Brett,Eaton ^[1] ; Michael,Murphy ^[1] ; Gregory,Kocher ^[1] ; Kyra,Hadley ^[1] ; Anthony E,Marketon ^[1] ; Rebecca M,Bernbaum ^[1] ; Amanda M W,Hischak ^[1] ; Randy,Hart ^[1] ; Nick,Vaughan ^[1] ; Jiro,Wada ^[1] ; Jing,Qin ^[2] ; Marisa C,St Claire ^[1] ; Connie S,Schmaljohn ^[1] ; Michael R,Holbrook ^[3]

作者单位： Integrated Research Facility at Fort Detrick, Division of Clinical Research (DCR), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Ft. Detrick, Frederick, MD, 21702, USA. ^[1] Biostatistics Research Branch (BRB), Division of Clinical Research (DCR), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, 20892, USA. ^[2] Integrated Research Facility at Fort Detrick, Division of Clinical Research (DCR), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Ft. Detrick, Frederick, MD, 21702, USA. Electronic address: michael.holbrook@nih.gov. ^[3]

关键词 Efficacy evaluation Hamster Natural history study therapeutic antibody SARS-CoV-2 Variants