Insights into the recognition of hypermucoviscous <i>Klebsiella pneumoniae</i> clinical isolates by innate immune lectins of the Siglec and galectin families.

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作者： María Asunción,Campanero-Rhodes ^[1] ; Sara,Martí ^[2] ; Noelia,Hernández-Ortiz ^[1] ; Meritxell,Cubero ^[2] ; June,Ereño-Orbea ^[3] ; Ana,Ardá ^[3] ; Jesús,Jiménez-Barbero ^[4] ; Carmen,Ardanuy ^[5] ; Dolores,Solís ^[1]

作者单位： Department of Biological Physical Chemistry, Instituto de Química Física Blas Cabrera, Consejo Superior de Investigaciones Científicas, Madrid, Spain.;Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain. ^[1] Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.;Microbiology Department, Hospital Universitari Bellvitge, University of Barcelona-Fundación Instituto de Investigación Biomédica de Bellvitge, L'Hospitalet de Llobregat, Spain. ^[2] CIC bioGUNE - Center for Cooperative Research in Biosciences, Basque Research & Technology Alliance (BRTA), Bizkaia Technology Park, Derio, Spain.;Ikerbasque, Basque Foundation for Science, Bilbao, Spain. ^[3] Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.;CIC bioGUNE - Center for Cooperative Research in Biosciences, Basque Research & Technology Alliance (BRTA), Bizkaia Technology Park, Derio, Spain.;Ikerbasque, Basque Foundation for Science, Bilbao, Spain.;Department of Organic Chemistry, II Faculty of Science and Technology University of the Basque Country, EHU/UPV, Leioa, Spain. ^[4] Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.;Microbiology Department, Hospital Universitari Bellvitge, University of Barcelona-Fundación Instituto de Investigación Biomédica de Bellvitge, L'Hospitalet de Llobregat, Spain.;Department of Pathology and Experimental Therapeutics, University of Barcelona, Barcelona, Spain. ^[5]

关键词 Klebsiella pneumoniae Siglecs bacterial cell surface carbohydrates galectins hypermucoviscosity lectins